01. Descamps O. Familial Hypercholesterolemia in Belgium

FAMILIAL
HYPERCHOLESTEROLE
MIA
President
Belgian Association of Patients
suffering from Familial
Hypercholesterolemia
Director
Lipid Clinic and Cardiovascular
Prevention
(Internal Medicine)
Center for Medicial Research.
Olivier Descamps, MD, PhD

Population: 3 wrong beliefs about
cholesterol !
«Cholesterol ?
»
= Adult-Problem
= Food-Problem
= Drug-Problem

!"#$#%&"'!&()'
48-yr-old man …
In coronary care unit
Admitted for myocardial
Infarctus
(mg/dl)
Total Cholesterol: 428
LDL-Cholesterol : 360
Triglycerides : 137
HDL-Cholesterol : 42
Equilibrated diet and physical
activity
Death 79 yrs
No CHD
LDL 152 mg/dL
Age 78 yrs
CHD 58 yrs
LDL 296 mg/dL
Age 48 yrs
CHD 48 yrs
LDL 360 mg/dL
Age 47 yrs
No CHD
LDL 96 mg/dL
Age 50 yrs
No CHD
LDL 131 mg/dL
Index case:
start of
cascade
screening
Age 18 yrs
LDL 88 mg/dL
Age 8 yrs
LDL 224 mg/dL
Age 15 yrs
LDL 244 mg/dL
FH FH
FH
FH
Man Woman
High suspicion
of Familial
Hypercholesterolemia

*&+#"#&"',-.)/%01")(2)/1")+#&'3*,4''

Doctors’ 3 wrong beliefs about
familial hypercholesterolemia !
«FH ? »
= A genetic
diagnosis !?
= We have time !?
= Rare !?