SYMPOSIUM ICSN 10-11 JUIN 2004 CANCER: TARGETS, MOLECULES AND THERAPIES

IXème SYMPOSIUM ICSN
« CANCER : CIBLES, MOLECULES ET THERAPIES »
CANCER: TARGETS, MOLECULES AND THERAPIES
10-11 JUIN 2004
Salle de la Terrasse, Gif-sur-Yvette, France
Scientific Committee : J.-Y. Lallemand, D. Louvard , P. Potier.
Organizing Committee: T. Cresteil, R.H. Dodd, D. Guénard, F. Guéritte, E. Guittet, E. Jacquet.
JEUDI 10 JUIN 2004
08H15 Accueil des participants (Greeting of participants)
09H00 Discours d’ouverture (Opening address) : Jean-Yves LALLEMAND
ASPECTS CLINIQUES : NOUVELLES STRATEGIES
CLINICAL ASPECTS : NEW STRATEGIES
CHAIRMAN : Jean-Yves LALLEMAND
09H15 – Michel MARTY (Institut Gustave Roussy, Paris, France)
“New Trends in Development of Antineoplastic Agents”
10H05 – Dominique BELLET (Université René Descartes, Paris , France)
« From Cancer Research to Drug Therapy!: Deciphering Advances from the Hype »
10H55 Pause/ Break
11H10 – Thierry CRESTEIL (ICSN-CNRS Gif-sur-Yvette, France)
“Activation/Inactivation of Anti-Cancer Drugs”
11h40 – Alain COMMERÇON (Aventis Pharma, Vitry-sur-Seine, France)
“Anticancer Drugs with Improved Targeting Properties”
12H30 – Repas/ Lunch
14H00 – Session Affiches / Poster Session

SUBSTANCES NATURELLES ET ANTICANCEREUX
NATURAL PRODUCTS AND ANTICANCER DRUGS
CHAIRMAN : Susan P. C. COLE
15H00 – Françoise GUÉRITTE (ICSN-CNRS, Gif-sur-Yvette, France)
« Natural Substances in Cancer Chemotherapy »
15H30 – Karl Heinz ALTMANN (Institute of Pharmaceutical Sciences, ETH, Zurich, Suisse)
“Epothilones as Lead Structures for Anticancer Drug Discovery”
16H20 – Pause/ Break
16H35 – Craig CREWS (Yale University, New Haven, USA )
« A Small Molecule Approach to Target Identification and Validation »
VENDREDI 11 JUIN 2004
NOUVELLES CIBLES (1)
NEW TARGETS (1)
CHAIRMAN : Daniel LOUVARD
09H15 – Susan P. C. COLE (Division of Cancer Biology & Genetics, Queen’s University, Kingston, Canada )
« An Update on the Structure and Pharmacology of the ABC
Drug and Organic Anion Transporter, MRP1.»
10H05 – John A. HICKMAN (Institut de Recherche SERVIER, Croissy-sur-Seine, France)
« Finding Molecular Targets for Cancer Chemotherapy »
10H55 – Pause/ Break
11H10 – Jacqueline CHERFILS (Lab. d’Enzymologie et Biochimie Structurale, CNRS , Gif-sur-Yvette, France)
« New Concepts for Inhibition of G Proteins »
12H00 – Jean-Yves LALLEMAND (ICSN-CNRS, Gif-sur-Yvette, France)
«! Cystic Fibrosis and Cancer : the Key Role of ABC Transporters»
12H30 – Repas/ Lunch

14H00 – Session Affiches / Poster Session
NOUVELLES CIBLES (2)
NEW TARGETS (2)
CHAIRMAN : Pierre POTIER
15H30 – Yves POMMIER (Laboratory of Molecular Pharmacology, NCI, Bethesda, USA)
« Genome Targeting with Topoisomerase Inhibitors »
16H20 – Anna KRUCZYNSKI (Laboratoire Pierre Fabre, Castres, France)
“Tafluposide, a Novel Inhibitor of Topoisomerases I and II,
Exhibits DNA Repair Inhibition Properties.”
17H10 – Daniel LOUVARD (Institut Curie, Paris, France)
« Applications of murin models of spontaneous intestinal tumors
for the development of new therapeutic approaches »
18H00 – Clôture / Closing remarks : Jean-Yves Lallemand
SITE!: http://www.icsn.cnrs-gif.fr