Le rôle essentiel des cellules endocrines de l`intestin

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Le#rôle#essentiel#des#cellules#endocrines#de#l’intestin#
Les#travaux#de#chercheurs#de#l’IGBMC#(unité#mixte#CNRS#/#Inserm#/#Université#de#Strasbourg)#
et# de# l’Unité# Inserm# U682# de# Strasbourg# publiés# dans# Journal# of# Clinical# Investigations,#
démontrent#pour#la#première#fois#que# les#cellules#endocrines#présentes#dans#le#tube#digestif#
sont#essentielles#à#la#vie.#
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Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and
impairs postnatal survival
Georg Mellitzer, Anthony Beucher, Viviane Lobstein, Pascal Michel, Sylvia Robine, Michèle
Kedinger, and Gérard Gradwohl
The Journal of Clinical Investigation Volume 120 Number 5 May 2010
Progéniteurs#endocrines#
(jaune)#exprimant#le#
facteur#de#transcription#
Neurogin3#dans#les#
cryptes#intestinales#
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Immunofluorescence,sur,coupe,
de,d’intestin,grêle,de,souris,
révélant,les,progéniteurs,
endocrines,exprimant,le,facteur,
de,transcription,Neurogenin3,
(rouge),dans,les,cryptes,
intestinales,et,les,cellules,
endocrines,à,,Sérotonine,(vert).,,
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