2015 - SFHTA

ISSN 0003-3928
Décembre 2015
Vol. 64
Hors-série 1
85706
35es Journées de l’Hypertension Artérielle
9th International Meeting of the French Society
of Hypertension
17-18 décembre 2015 – Palais des Congrès de Paris
Livre des résumés

ANNALES DE CARDIOLOGIE ET D’ANGÉIOLOGIE Vol. 64/ Hors-série 1 (2015) S1-S106

© Elsevier Masson SAS. All rights reserved.
Annales de cardiologie et d’angéiologie 64 (2015) S1-S2
35
es
Journées de l’Hypertension Artérielle
9
th
International Meeting of the French Society of Hypertension
SOMMAIRE
COMMUNICATIONS ORALES
Cœur et Vaisseaux 1 / Heart and vessels 1
17/12/2015 – 14:00 – 15:30
CO-01 à CO-05 ................................................................................................................................................................. S3
Clinique 1 / Clinics 1
17/12/2015 – 14:00 – 16:00
CO-06 à CO-12 ................................................................................................................................................................. S5
Épidémiologie / Epidemiology
17/12/2015 – 16:30 – 18:00
CO-13 à CO-17 ................................................................................................................................................................. S8
Clinique 2 / Clinics 2
17/12/2015 – 16:30 – 18:00
CO-18 à CO-22 ................................................................................................................................................................. S10
Thérapeutique, Mesure de la PA, Pharmacologie / Therapeutics, BP Measurement, Pharmacology
17/12/2015 – 16:30 – 18:00
CO-23 à CO-27 ................................................................................................................................................................. S12
Cœur et Vaisseaux 2 / Heart and vessels 2
18/12/2015 – 08:30 – 10:00
CO-28 à CO-32 ................................................................................................................................................................. S13
Hormones, Génétique, HTA Expérimentale / Hormones, Genetics, Secondary Hypertension
18/12/2015 – 10:30 – 12:00
CO-33 à CO-37 ................................................................................................................................................................. S16
Rein et Système Nerveux / Kidney and Nervous System
18/12/2015 – 10:30 – 12:00
CO-38 à CO-42 ................................................................................................................................................................. S18
Session Hot Topics / Hot Topics Session
18/12/2015 – 14:00 – 15:30
CO-43 à CO-46 ................................................................................................................................................................. S20

© Elsevier Masson SAS. All rights reserved.
S2 Annales de cardiologie et d’angéiologie 64 (2015), S1-S2
SESSIONS MEILLEURES POSTERS
Session 1
17/12/2015 – 16:00 – 16:30
P1-01 à P1-10 ....................................................................................................................................................................S23
Session 2
17/12/2015 – 16:00 – 16:30
P2-11 à P2-18 ....................................................................................................................................................................S27
Session 3
18/12/2015 – 10:00 – 10:30
P3-19 à P3-27 ....................................................................................................................................................................S29
Session 4
18/12/2015 – 10:00 – 10:30
P4-28 à P4-36 ....................................................................................................................................................................S32
POSTERS AFFICHES
Clinique / Clinics
......................................................................................................................................................... S37
Cœur et Vaisseaux / Heart and vessels .................................................................................................................. S50
Epidémiologie / Epidemiology .................................................................................................................................. S63
Génétique / Genetics ................................................................................................................................................... S75
Hormones / Hormones ................................................................................................................................................ S76
HTA Expérimentale / Experimental Hypertension ............................................................................................ S78
Mesure de la PA / BP Measurement ....................................................................................................................... S79
Pharmacologie / Pharmacology ...............................................................................................................................S82
Rein / Kidney ................................................................................................................................................................ S83
Système Nerveux / Nervous System ........................................................................................................................ S93
Thérapeutique / Therapeutics .................................................................................................................................. S95
PROGRAMME INFIRMIERES
Ateliers
............................................................................................................................................................................. S99
Formation pratique infirmières ................................................................................................................................ S100
INDEX DES AUTEURS ............................................................................................................................................. S101
Certaines données publiées dans cette édition spéciale peuvent ne pas avoir été validées
par les autorités françaises.
La publication de ce contenu est effectuée sous l’égide et la seule responsabilité
de la Société française d’hypertension artérielle (SFHTA).

© Elsevier Masson SAS. All rights reserved.
Annales de cardiologie et d’angéiologie 64 (2015) S3-S22
35
es
Journées de l’Hypertension Artérielle
9
th
International Meeting of the French Society of Hypertension
COMMUNICATIONS ORALES
CO 01 Cœur et vaisseaux / Heart and vessels
CO-01
Retinal arterioles remodeling evaluated by adaptive optics camera in
humans and its relationships with age, blood pressure and cardio-
vascular risk factors
Le remodelage des artérioles rétiniennes chez les humains étudié par
l’optique adaptative et ses relations avec l’âge, la pression et les fac-
teurs de risque cardiovasculaire
D. ROSENBAUM
1
, A. MATTINA
1
, E. KOCH
2
, F. ROSSANT
3
,
A. GALLO
1
, N. KACHENOURA
2
, M. PAQUES
2
, A. REDHEUIL
3
,
X. GIRERD
1
1
Unité de Prévention des Maladies Cardiovasculaires, Pr Bruckert, Hôpi-
tal Pitié-Salpetrière, AP-HP, Paris, France.
2
Unité Inserm 968, Institut de la Vision, CIC 503, Centre Hospitalier
National DES 15/20, AP-HP, Paris, France.
3
Sorbonne Université, UMPC Univ. Paris 06, CNRS 7371, Laboratoire
d’Imagerie Biomédicale, Paris, France.
Background Microvascular vessels and microvascular remodeling play a
major role in blood pressure (BP) regulation and peripheral tissue oxygen
delivery. The adaptive optics camera (AOC), a novel technique of fundus
image analysis enables the noninvasive characterization of microvascular
remodeling in the retina on a large scale. Our objective was to assess the role
of Blood Pressure (BP), ageing, diabetes and other risk factors on retinal arte-
riolar remodeling using AOC.
Methods In 1.000 consecutive subjects in primary prevention with risk
factors, we used the new RTX1
®
AOC (Imagine-Eyes, Orsay, France) and
a semi-automated segmentation software to measure Wall Thickness (WT),
Internal Diameter (ID) and to calculate Wall-to-Lumen Ratio (WLR) and
Wall Cross Sectional Area (WCSA) on retinal arteriolar microvasculature.
BP was assessed on standard conditions using oscillometric device during
the AOC assessment. Hypertension was defined as the presence of Systolic
BP>140mmHg and/or Diastolic BP>90mmHg. Standardized clinical and
biological examinations were performed to assess for the presence of dia-
betes, dyslipidemia, obesity and current smoking which were defined
according to guidelines.
Results Overall, ageing was associated with an increase in WLR due to
sole WT increase. Subjects with office hypertension (n=313) had inward
eutrophic remodeling with increased WLR (0.325±0.049 vs 0.292±0.056) due
JEUDI 17 DÉCEMBRE 2015
14:00 – 15:30
Retinal Arteriolar Microvasculature Blood Pressure
N WLR ID.-μm WT.-μm WCSA.-μm
2
Systolic BP.-MmHg Diastolic BP.-MmHg
Gender
Female 489 0.301 ± .0.50 79.0 ± 10.9 23.5 ± 3.6 3386 ± 817* 129.5 ± 21.2 72.2 ± 13.7
Male 511 0.300 ± .0.57 77.3 ± 11.1 22.89 ± 4.2 3234 ± 886 132.2 ± 19.4 71.5 ± 13.8
Hypertension
Yes 313 0.325 ± .0.49 ‡ 75.6 ± 10.9 † 24.2 ± 4.0 ‡ 3392 ± 832 153.1 ± 16.1 ‡ 82.1 ± 14.8 ‡
No 687 0.292 ± .0.56 78.6 ± 10.8 22.7 ± 3.6 3249 ± 873 120.8 ± 12.4 67.1 ± 10.3
Diabetes
Yes 180 0.308 ± .0.52 79.5 ± 11.2 24.2 ± 3.8 ‡ 3523 ± 861† 134.4 ± 19.6 70.8 ± 13.6
No 820 0.299 ± .0.55 77.8 ± 11.2 23.0 ± 3.9 3256 ± 844 130.2 ± 20.5 72.1 ± 13.9
Dyslipidemia
Yes 436 0.301 ± .0.57 77.6 ± 11.1 23.3 ± 4.1 3333 ± 828 130.4 ± 20.0 69.4 ± 12.2 ‡
No 564 0.301 ± .0.53 78.6 ± 11.1 23.2 ± 3.7 3281 ± 886 131.3 ± 20.6 73.7 ± 14.6
Obesity
Yes 164 0.303 ± .0.55 77.0 ± 11.4 23.2 ± 3.9 3255 ± 838 136.1 ± 20.3 ‡ 76.3 ± 13.2 ‡
No 836 0.300 ± .0.55 78.2 ± 10.8 23.1 ± 3.9 3307 ± 838 129.3 ± 20.3 70.5 ± 13.7
WLR is Wall-to-Lumen Ratio, ID is internal Diameter, WT is Wall Thickness, WCSA is Wall Cross Sectionnal Area, BP is blood pressure * p<.01, † p<001
‡ p<.0001 between groups