(ULB 1986), spécialiste en Médecine Interne.

Bernard Corvilain CV Resume 09-2002 1
Sept. 2002
CV RESUME
Bernard Corvilain, MD PhD.
DOB 05 Aug 1959.
Professional address: Service d'Endocrinologie, Hôpital Erasme – ULB, 808 Route de
Lennik, 1070 Bruxelles.
Ph : +322-555.3407
Fax: [phone]
[email protected]
Current positions
−
−−
− Faculty Physician (Chef de Clinique Adjoint), Service d'Endocrinologie, Hôpital Erasme –
ULB (Université Libre de Bruxelles).
−
−−
− Member of the board of the Belgian Thyroid Club
Training, graduations, and former activities
Doctor of Medecine (MD) ULB 1984
Specialist of Internal Medicine, 1992.
PhD Thesis ("Agrégation de l'Enseignement Supérieur") ULB, 1995.
Research fellowship Fondation Erasme, 1987-1988
Research Assistant, Belgian FNRS, 1988-1990.
Research fellowship Fondation Erasme, 1998-1999

Bernard Corvilain CV Resume 09-2002 2
Publications:
1. CORVILAIN, B., VAN SANDE, J., DUMONT, J.E.
Inhibition by iodide of iodide binding to proteins : the "Wolff-Chaikoff" effect is
caused by inhibition of H202 generation.
Biochemical and Biophysical Research communications, 154, 1287-1292, 1988.
2. GOLSTEIN, J., CORVILAIN, B., LAMY, F., PAQUER, D., DUMONT, J.E.
Effects of a selenium deficient diet on thyroid function of normal and perchlorate
treated rats.
Acta Endocrinologica 118, 495-502, 1988.
3. J.E. DUMONT, CORVILAIN, B., COCLET, J., RASPE, E., REUSE, S.
Recent Progress in Fundamental Thyroidology with Relevance to the Prevention of
Medical Consequences of a Nuclear Accident.
In : Iodine Prophylaxis Following Nuclear Accidents.
Pergamon Press, 32-37, 1988.
4. RASPE, E., REUSE, S., MAENHOUT, C., ROGER, P., CORVILAIN, B.,
LAURENT, E., MOCKEL, J., LAMY, F., VAN SANDE, J., DUMONT, J.E.
Importance and variability of transducing systems in the control of thyroid cell
function, proliferation and differentiation.
In : Growth regulation of thyroid gland and thyroid tumors. Eds Goretzki, P.E.,
Röher, H.D., Frontiers in Hormones Research. 18, 1-13, 1989.
5. DUMONT, J.E., LEFORT, A., LIBERT, F., PARMENTIER, M., RASPE,
E., REUSE, S., MAENHOUT, C., ROGER, P., CORVILAIN, B., LAURENT, E.,
MOCKEL, J., LAMY, F., VASSART, G.
Transducing systems in the control of human thyroid cell function, proliferation
and differentiation.
In : Control of the thyroid gland. Eds Ekholm, R., Kohn, D., Wollman, S.H.
Adv. Exp. Med. Biology, 261, 357-372, 1989.
6. VAN SANDE, J., CORVILAIN, B., LAURENT, E., LEJEUNE, C., ROCMANS,
P., MOCKEL, J., DUMONT, J.E.
The biochemistry of autonomous thyroid nodules : clues on the pathogenesis.
Acta Medica Austriaca, (1), 15-17, 1990.
7. MAENHAUT, C., LEFORT, A., LIBERT, F., PARMENTIER, M., RASPE,E.,
ROGER, P.,CORVILAIN, B, LAURENT, E., REUSE, S., MOCKEL, J., LAMY, F.,
VAN SANDE, J., DUMONT, J.E.
Function, proliferation and differentiation of the dog and human thyrocyte.
in : Physiological regulation and biological function of thyreotropin. Eds. Pfeiffer
E.F., Reaven G.M.
Horm. Metab.Res. 23, 51 - 61, 1990.

Bernard Corvilain CV Resume 09-2002 3
8. REUSE, S., MAENHAUT, C., LEFORT, A., LIBERT, F., PARMENTIER,M.,
RASPE, E., ROGER, P., CORVILAIN, B., LAURENT, E., MOCKEL, J.,
LAMY, F., VANSANDE, J., VASSART, G., DUMONT, J.E.
The control of human thyroid cell function, proliferation and differentiation.
in : Activation and desensitization of transducing pathways.Eds. Konijn T.M.,
Houslay M.D., Van Haastert P.J.M.
NATO ASI Series. H 44, 285 - 306, 1990.
9. CORVILAIN, B., GERARD, C., RASPE, E., LEFORT, A., MOCKEL, J., VAN
SANDE, J., DUMONT, J.E.
Hormonal regulation of iodination.
in : Thyroperoxidase and thyroid autoimmunity. Ed. Carayon P., Ruf. J.
INSERM - 207, 33 - 41, 1990.
10. LAURENT, E., VAN SANDE, J., LUDGATE, M., CORVILAIN, B.,
ROCMANS, P., MOCKEL, J.
Unlike thyrotropin, thyroid stimulating antibodies do not activate phospholipase C
in human thyroid slices.
J. Clin. Invest., 87, 1634-1642, 1991.
11. CORVILAIN, B., VAN SANDE, J., LAURENT, E., DUMONT, J.E.
The H2O2 generating system modulates protein iodination and the activity of the
pentose phosphate pathway in dog thyroid.
Endocrinology, 128, 779-785, 1991.
12. RASPE, E., LAURENT, E., CORVILAIN, B., VERJANS, B., ERNEUX, C.,
DUMONT, JE.
Control of the Intracellular Ca²+-Concentration and the Inositol Phosphate
Accumulation in Dog Thyrocyte Primary Culture : Evidence for Different
Kinetics of Ca²+-Phosphatidylinositol Cascade Activation and for Involvement
in the Regulation of H2O2 Production
Journal of Cell. Physiology, 250, 242-250, 1991.
13. CORVILAIN, B.
Clinical problem-solving : how sure is sure enough ?
N. Engl. J. Med., 327 (5), 360, 1992. (Letter)
14. CORVILAIN, B., CONTEMPRE, B., VANDERPAS, J., DUMONT, JE.
Crétinisme, métabolisme thyroïdien et sélénium.
Rev. Franç. Endocrinol. Clin. 33 n° 3, 181-189, 1992.
15. DUMONT, JE., CORVILAIN, B.
Régulation de l'hormonogénèse par la TSH (Chapitre de livre).
in : La thyroïde. Expansion scientifique française.
Eds. Leclere J. et al. 80-83, 1992

Bernard Corvilain CV Resume 09-2002 4
16. CORVILAIN, B., MATTE, J., LITVINE, C.
Serum cholesterol in young men and cardiovascular disease.
N. Engl. J. Med., 329 (2), 138, 1993. (Letter)
17. CORVILAIN, B., CONTEMPRE, B., LONGOMBE, AO., GOYENS, P.,
GERVY-DECOSTER, C., LAMY, F.
Selenium and the thyroid : how the relationship was established.
Am. J. Clin. Nutr. 57 (2 suppl.) : 244S-248S, 1993.
18. DUMONT, JE., CORVILAIN, B, CONTEMPRE, B.
The biochemistry of endemic cretinism: roles of iodine and selenium
deficiency and goitrogens
Mol. Cell. Endocrinol. 100, 163-166, 1994
19. CORVILAIN, B., LAURENT, E., LECOMTE, M., VAN SANDE,
J.,DUMONT, JE.
Role of the cyclic AMP and the PIP2 cascades in mediating the effects of
thyrotropin and iodide on hormone synthesis and secretion in human thyroid
slices.
J. Clin. Endocrinol. Metab., 79, 152-159, 1994.
20. CORVILAIN, B., ABRAMOWICZ, M., FERY, F., SCHOUTENS, A.,
VERLINDEN, M., BALASSE, EO., HOROWITZ, M.
Effects of short term fasting on gastric emptying in normal and obese
subjects. Relationship to oral glucose tolerance test.
Am. J. of Physiology: 269:G512-G517, 1995
21. CORVILAIN, B., CONTEMPRE, B., MOCKEL J., ERMANS AM.,
DUMONT, JE.
Autonomie thyroïdienne et goitre endémique.
Rev. Franç. Endocrinol. Clin. 38 n° 3, 197-207, 1997.
22. CORVILAIN, B., SCHINOHORITIS, P.
Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids
Postgrad Med J: 73:686, 1997 (Letter)
23. CORVILAIN, B., VAN SANDE, J.,DUMONT, JE., BOURDOUX P,
ERMANS AM.
Autonomy in endemic goiter.
Thyroid, 8(1):107-13, 1998
24. COTTON F, SORLIN P, CORVILAIN B, FOCKEDEY JM, CAPEL P.
Interference with oral anticoagulant treatment by oestrogen--influence of
oestrogen administration route.
Thromb Haemost Mar;81(3):471-2, 1999 (Letter)
25. CORVILAIN B, COLLYN L, VAN SANDE J, DUMONT JE.
Stimulation by iodide of H2O2 generation in thyroid slices from several species.
Am.J.Physiol. 2000 Apr;278(4):E692-9, 2000

Bernard Corvilain CV Resume 09-2002 5
26 CORVILAIN B, DUMONT JE, VASSART GToxic Adenoma and Toxic
Multinodular goiter (Book chapter)
In: The Thyroid 8th Edition
LE Brawerman and RD Utiger Editors
Lippincott-Raven Publishers
564-572, 2000
27. DELEU S, ALLORY Y, RADULESCU A, PIRSON I, CARRASCO N,
CORVILAIN B, SALMON I, FRANC B, DUMONT JE, VAN SANDE J,
MAENHAUT C
Characterization of autonomous thyroid adenoma: metabolism, gene expression and
pathology. Thyroid. Feb;10(2):131-40, 2000
28. CORVILAIN,B.; VAN SANDE,J.; DUMONT,J.E.; VASSART,G.Somatic and
Somatic and germline mutations of the TSH receptor and thyroid diseases
Clin Endocrinol (Oxford) 55 (2) 143-158, 2001
29. CORVILAIN B, VAN SANDE J, MOCKEL J, DUMONT JE
Régulation de la synthèse et de la sécrétion des hormones thyroïdiennes
l'hormonogénèse par la TSH. (Chapitre de livre)
In : La thyroïde. Des concepts à la pratique clinique 2ème Edition
Eds. Leclere J. et al.
Elsevier Publisher.
84-86, 2001
30. VAN SANDE J, BOEYNAEMS JM, CORVILAIN B, DUMONT JE
Régulation de la fonction thyroïdienne par l'iode. (Chapitre de livre)
In : La thyroïde. Des concepts à la pratique clinique 2ème Edition
Eds. Leclere J. et al.
Elsevier Publisher.
101-102, 2001
31. MORENO-REYES R, CORVILAIN B.
Amiodarone induced thyroiditis (Letter)
Lancet 2002 Jun 29;359(9325):2276