3rd International IMBG Meeting on Metals in Health and Environment

3rd International IMBG Meeting on Metals in Health and
Environment
Autrans
du 22 au 24 septembre 2008
Monday 22th. - Morning session
8 :30 - 9 :00
Stéphane Ménage
Welcome
Chair:
9:00 - 9:45
Bibudhendra Sarkar (The Hospital for Sick Children,
Toronto, Canada)
Genetic Defects of Copper Transport: Wilson and Menkes
diseases”
9:45 - 10:15
Murielle Bost (Centre Maladie Rare, Bron, France)
Wilson disease, a copper disorder: an update
Coffee break
10:45 - 11:15
Michel Seve (Centre d'Innovation en Biologie, Grenoble,
France)
Mammalian Zinc transporters: With a special focus on Zinc
transporter 8 (SLC30A8) and diabetes: a promising new
diagnostic and therapeutic target
11:15 - 11:45
Ulrich Schweizer (Neuroscience Research Center, Berlin,
Germany)
How does selenium enter the brain and what does it do there?
11:45 - 12:15
Isabelle Michaud-Soret (Lab Chimie et Biologie des
Métaux, Grenoble)
Inhibition of the global metalloregulator Fur (ferric uptake
regulator) with anti-FUR peptide aptamers.
Monday 22th. - Afternoon session
Chair:
14:15 - 15:00
Alain Favier (University of Grenoble, CEA, INAC, SCIBLAN)
Carcinogenic effect of metals is related not only to but their
induction of DNA damages but also to their inhibition of
DNA repair.
15:00 - 15:30
Peggy L. Carver (University of Michigan, Ann Arbor, MI,
USA)
Plasma Concentrations of Trace Metal Ions and their
Correlation with Infection in Patients Undergoing Long-Term
Home Total Parenteral Nutrition (TPN).
15:30 - 16:00
B. Gyurcsik (University of Szeged, Hungary)
Chimeric metallonucleases for gene theraphy.
Coffee Break
16:30 - 17:00
17:00 - 17:30
Joël Poupon
Josiane Arnaud (CHU de Grenoble, Pôle de Biologie)
Are plasma copper, zinc and selenium concentrations
modified in Metabolic Syndrome? The Immidiet Project
POSTER SESSION (à 19:30)
Tuesday 23th - Morning session
Chair:
8:30 - 9:15
Peter Sadler (Department of Chemistry, University of Warwick,
UK)
Design of therapeutic metal complexes
9:15 - 9:45
Éva J. Tóth (Centre de Biophysique Moléculaire, Orléans
France)
Smart contrast agents in Magnetic Resonance Imaging:
detecting calcium fluctuations and enzymatic activity.
9:45 - 10:15
Pascale Delangle (CEA Grenoble)
Gd3+ complexes derived from natural molecules: coordination
and water proton relaxation properties
Coffee break
10:45 - 11:15
Lukeš, I (Universita Karlova, Prague, Czech Republic)
Gd(III) Based Contrast Agents for MRI: Molecular Volume
vs. Efficiency.
11:15 - 11:45
Peter Faller (Lab. de Chimie de Coordination du CNRS,
Toulouse, France)
Metals in Alzheimer’s Disease: Bioinorganic Chemistry of
Amyloid-β
11:45 - 12:15
Daniella Valensin (University of Siena, Italy)
Zn2+ and Cu2+ Interactions with Rat and Human βAmyloid
(1-28) peptides in H2O/SDS Solutions by NMR and CD
spectroscopy.
Tuesday 23th - Afternoon session
Chair:
14:15 - 15:00
Silvio Aime (Det. of Chem. & Mol. Imaging Center Univ. of
Torino, Italy)
Metal containing Nano-sized Systems for MR-Molecular
Imaging Applications
15:00 - 15:30
Tamim Chalati (Institut Lavoisier, Université de Versailles,
France)
Nanoparticles of Porous Iron Carboxylates as New Drug
Carriers
15:30 - 16:00
Marion Giraud (Institut de Nanosciences et Cryogénie,
CEA-Grenoble)
Tuning the properties of lanthanides probes through ligand
design.
Coffee break
16:30 - 17:00
Vincent Pecoraro (University of Michigan, Ann Arbor, MI,
USA)
De Novo Design of Heterochromic and Diastereomeric
Metalloproteins.
17:00 - 17:30
Gérard Jaouen (Ecole Nationale Supérieure de Chimie de
Paris)
Activation of polyphenols via an intramolecular
organometallic "antenna": biomedical applications.
POSTER SESSION (à 7:00)
Wednesday 24th
Chair:
8:30 - 9:15
Carlo Barbante (Dpt. of Environmental Sciences, Univ. of
Venice, Italy)
The History of Heavy Metal Pollution Revealed by Polar and
Alpine Ice.
9:15 - 9:45
Isabelle Schalk (University Louis Pasteur, Strasbourg,
France)
The metal specificities of the Pseudomonas aeruginosa
siderophore-iron uptake pathways: tools for bioaugmentationassisted phytoextraction
9:45 - 10:15
Michel Meyer (Institut de Chimie Moléculaire, Dijon,
France)
Silica-gel-bound macrocycles: A molecular approach to
remove lead from drinking water.
Coffee break
10:45 - 11:15
Kirstin Adriaensen (Hasselt Univ., Environmental Biology
Group, Belgium)
Mechanisms of metal sequestration in the metal tolerant
ectomycorrhizal fungus Suillus sp.
11:15 - 11:45
Jacques Covès (Institut de Biologie Structurale, Grenoble)
CopH and CzcE, two novel periplasmic proteins from
Cupriavidus metallidurans CH34 with unusual modes of
copper binding.
11:45 - 12:15
Sylvain Bohic (Institut des Neurosciences, Grenoble)
Synchrotron based spectro-microscopy for cell biology.