POLE HOSPITALIER D.A.C.C.O.R.D. (Digestif, Anatomie
publicité
POLE HOSPITALIER D.A.C.C.O.R.D. (Digestif, Anatomie-pathologique, Chirurgie, CISIH, Oncologie, Radiothérapie, Dermatologie) CHEF DE PÔLE : Pr Jean François SEITZ ADRESSE : Service d’oncologie digestive 12ème étage Timone adulte TELEPHONE : 04 91 38 85 16 COURRIEL : [email protected] ECOLE DOCTORALE : MEDECINE RATTACHEMENTS : Université Aix-Marseille-CRO2 DISCIPLINES D’APPARTENANCES : sous section n°52-01 SPECIALITÉS : Hépato Gastro entérologie Cancérologie EFFECTIFS Enseignants-Chercheurs (PU-PH, MCU-PH, CCA, AHU): PU PH : 6 ETP - D. COWEN D.FIGARELLABRANGER L.DANIEL B. SASTRE I.SIELEZNEFF N.PIRRO J.J.GROB M.A RICHARD J.F. SEITZ F.DUFFAUD P.NICCOLI MCU-PH : 2.5 ETP C.PAGIS H.LEPIDI C.LAPIT M.OUAISSI C.GAUDY PHU : 0.5ETP L.DAHAN CCA : 4.5ETP A. ZACCARIOTTO T.DUBERGE V.LATRASSE A.BENOIST D’AZY A. LEVYBENCHETON E. NORGUET J.L. DEVILLE T.K. HUYNH G. BOUDOUX D’HAUTEFEUILL E Pôle hospitalier. D.A.C.C.O.R.D. AHU : 1 ETP J. TORRENTS MAUES DE PAULA 1/22 Personnel Hospitalier (PH, Attaché) : PH TEMPS PARTIEL:1ETP PH TEMPS PLEIN:16ETP D. BADINAND L.PADOVANI A.M TASEI M.C. ROJAT B. CONSENTINO B BERTHET S.HESSE S.MONESTIER D.MONGES P.RIES A. NICOARA S.SALAS C.DUPUIS P.GRANDVAL I.POIZOT-MARTIN X. MURACCIOLE A.M. COLLET-VILLETTE PH CONTRACTUEL:4.2ETP A.MENARD D.BACCONNIER C. CHAMPETIER J.DEL GRANDE M. DULUC S.RONOT-BREGIGEON ATTACHE:12.93 ETP C.AQUARON S.FAUQUIER A.LARROQUE I.M.NICOL L.SARDA P.LE NOUAIL C.KAROUTCHI S.MALLET F.REPELLIN S.FOURCADE D.GOZLAN S.RANQUE G.ANTONI E.BAREL M.GALLART D.HUGUES Z.NIKOLAJEVIC B.MARCHETTI J.CESARI M.PERREARD E.ABOU A.LAQUIERE S.CRESTI C.BOUSTIERE C.ROUSSET T.GAMBY D.BOURDET I.GAUTIER A.N.MURACCIOLE H.BERTONE A.EMRAM F.BRUN M.CASTELAIN M.ORTICONI E.ARNAUD J.CARMANTRAND V.LIABEUF P.DUKAN J.PONTE O.RONSIN R.LAURANS J.ALLEMAND S.LA GRASSA M.J.DUCASSOU S.BERTRAND O.ZAEGEL N.QUILES Pôle hospitalier. D.A.C.C.O.R.D. 2/22 Personnel Technique : 15.65 ETP (Ingenieur de Recherche, Ingenieur en Chef, Ingenieur Hospitalier, Technicien supérieur contractuel, Technicien superieur hospitalier, Agent d'Entretien Qualifie, Maitre Ouvrier Ouvrier Professionnel Qualifie) Personnel Administratif : 46.7 ETP (Adjoints administratifs, secrétaires médicales et attachée d’administration Hospitalière) Etudiants : - Externes:48 E.BONNET F.HIRON A.BRUN A.E.LEININGER S.F.LAURENT M.A.RAUMEL P.LEROUX A.O.MARTIN J.B.REY A.LOPEZ B.COULON M.PEREZ R.MALLI J.SIGRAND R.POROT J.CHAN YU KING D.HEPAKCIN G.S.DENIS C.GUIS P.PIERRIN H.HOURS J.HADJADJE J.GRAZIANI J.GUINDE M.DELANDRE C.BLANC D.HAMON M.JUZAUD N.PAILHES A.LE SAUX A.GUILPAIN L.DUVAL S.B.LE SERRE E.GASCHE L.ZAHRA M.GAUBERT M.CAMPANA H.HERRERO G.MARTIN R.CAYUELA H.ALLANIC J.DAVIN L.LIMIDO H.M.FALQUE T.A.GARRIVIER G.HERRERA E.M.ACCARIER - Internes: 33 M.FAURE C.SERVAJEAN M.CELHAIGUIBEL T.ARRIGHI M.A.S.MEURER M.CHEHAT K.MARCHI P.ROCHIGNEUX M.RIOU SAUVE L.DUJOUR E.RALLO V.SCARPELLINI C.TOULLEC C.GIACINO G.BOOKER S.GONZALEZ Pôle hospitalier. D.A.C.C.O.R.D. 3/22 PERSONNELS RATTACHÉS A UNE EQUIPE DE RECHERCHE Chinot Olivier Figarella-Branger Dominique Daniel Laurent Bouvier Corinne Dahan Laeticia Seitz Jean françois Ouafik L’Houcine Chef de service Chef de service Chef de Service Chef de Service Salas Sébastien Deville Jean Laurent Sielezneff Igor INSERM UMR 911 INSERM UMR 911 CRO2 INSERM UMR 911 CRO2 INSERM UMR 911 CRO2 INSERM UMR 911 CRO2 CRO2 – INSERM 911 SERVICES HOSPITALIERS INTITULÉ : CISIH RESPONSABLE : Dr I. POIZOT-MARTIN DISCIPLINE : MEDECINE INTITULÉ : CHIRURGIE DIGESTIVE TA RESPONSABLE : Pr B. SASTRE DISCIPLINE : CHIRURGIE INTITULÉ : DERMATOLOGIE-VENEROLOGIE RESPONSABLE : Pr J.J. GROB DISCIPLINE : MEDECINE INTITULÉ : LABORATOIRE D’ANATOMIE-PATHOLOGIQUE RESPONSABLE : Pr D. FIGARELLA-BRANGER DISCIPLINE : MEDECINE INTITULÉ : LABORATOIRE D’ONCOLOGIE BIOLOGIQUE RESPONSABLE : Pr H. OUAFIK DISCIPLINE : MEDICO-TECHNIQUE INTITULÉ : NEURO ONCOLOGIE RESPONSABLE : Pr O. CHINOT DISCIPLINE : MEDECINE INTITULÉ : ONCOLOGIE DIGESTIVE RESPONSABLE : ONCOLOGIE MEDICALE DISCIPLINE : MEDECINE INTITULÉ : ONCOLOGIE MEDICALE RESPONSABLE : Pr DUFFAUD DISCIPLINE : MEDECINE INTITULÉ : RADIOTHERAPIE RESPONSABLE : Pr D. COWEN DISCIPLINE : MEDICO-TECHNIQUE Pôle hospitalier. D.A.C.C.O.R.D. 4/22 PUBLICATIONS ANNÉES 2010 et 2011 ANNÉE 2010 Raynaud S, Carbuccia N, Colin C, Adélaïde J, Mozziconacci MJ, Metellus P, et al. Absence of R140Q mutation of isocitrate dehydrogenase 2 in gliomas and breast cancers. Oncol Lett 2010;1:883-884. Boissier R, Gross E. La radiothérapie hypofractionnée dans le traitement du cancer de prostate : irradier moins pour traiter plus. Prog Urol 2010; 22:326-30. Duffaud F, Salas S, Huyn T, Deville J. Imatinib as the first and only treatment in Europe for adult patients at significant risk of relapse following gastrointestinal stromal tumor removal. Clin Exp Gastroenterol 2010; 3:41-7. Barbut J, Fernandez C, Blanc F, Dubus JC, Guys JM, de Lagausie P. Pulmonary sequestration of the left upper lobe associated with a bronchogenic cyst: Case report of an exceptional association. Pediatr Pulmonol 2010 . Richard MA. Alitrétinoïne et eczéma chronique des mains: synthèse des essais cliniques. Ann Dermatol Venereol 2010; 137 Suppl 3:S111-23. Llorca PM, Courtet P, Martin P, Abbar M, Gay C, Meynard JA, et al. Dépistage et prise en charge du trouble bipolaire : résultats. Encephale 2010;36 Suppl 4:S86-102. Llorca PM, Courtet P, Martin P, Abbar M, Gay C, Meynard JA, et al. Dépistage et prise en charge du trouble bipolaire : méthodologie. Encephale 2010;36 Suppl 4:S79-85. Serratrice G, Pellissier JF, Serra-Trice J, Weiller PJ. Les canalopathies potassiques, autour du syndrome de Morvan. Bull Acad Natl Med 2010; 194:391-406; discussion 406-7. Bennani B, Gilles S, Fina F, Nanni I, Ibrahimi SA, Riffi AA, et al. Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer. Int J Biol Markers 2010;25:179-84. Gross E, Champetier C, Pointreau Y, Zaccariotto A, Dubergé T, Chauvet B. Séminomes testiculaire de stade 1. Cancer Radiother 2010; 14 Suppl 1:S182-8. Bennani B, Gilles S, Fina F, Nanni I, Ibrahimi SA, Riffi AA, et al. Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer. Int J Biol Markers 2010;25. Sabatier R, Bouvier C, de Pinieux G, Sarran A, Brenot-Rossi I, Pedeutour F, et al. Lowgrade extraskeletal osteosarcoma of the chest wall: case report and review of literature. BMC Cancer 2010;10:645. Metellus P, Coulibaly B, Colin C, de Paula AM, Vasiljevic A, Taieb D, et al. Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis. Acta Neuropathol 2010; 120:719-29 . Hoffart L, Matonti F, Conrath J, Daniel L, Ridings B, Masson GS, et al. Inhibition of corneal neovascularization after alkali burn: comparison of different doses of bevacizumab in monotherapy or associated with dexamethasone. Clin Experiment Ophthalmol 2010;38:346-52. Chinot O, Soulier P, Frenay M. Chimiothérapie et traitements ciblés des glioblastomes. Neurochirurgie 2010;56:491-8. Pôle hospitalier. D.A.C.C.O.R.D. 5/22 Loko MA, Salmon D, Carrieri P, Winnock M, Mora M, Merchadou L, et al. The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): early findings, 2006-2010. BMC Infect Dis 2010;10:303. Duffaud F, Salas S, Huynh T. Recent advances in the management of gastrointestinal stromal tumors. F1000 Med Rep 2010;2 . Dahan L, Bonnetain F, Ychou M, Mitry E, Gasmi M, Raoul JL, et al. Combination 5fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301). Gut 2010; 59:1527-34 . Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, et al. Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. J Clin Oncol 2010; 28:4961-8 . Régis J, Muracciole X. Associated is not induced! World Neurosurg 2010;73:642-3. Ciccolini J, Gross E, Dahan L, Lacarelle B, Mercier C. Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope? Clin Colorectal Cancer 2010;9:224-8 . Dia A, Gautret P, Adheossi E, Bienaimé A, Gaillard C, Simon F, et al. Illness in French travelers to Senegal: prospective cohort follow-up and sentinel surveillance data. J Travel Med 2010; 17:296-302 . Hoskins C, Ouaissi M, Lima SC, Cheng WP, Loureirio I, Mas E, et al. In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer. Pharm Res 2010;27:2694-703. Le Cesne A, Ray-Coquard I, Bui BN, Adenis A, Rios M, Bertucci F, et al. Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial. Lancet Oncol 2010;11:9429. Figarella-Branger D, Bouvier C, Moroch J, Michalak S, F Burel-Vandenbos . Classification morphologique des glioblastomes. Neurochirurgie 2010;56:459-63 . Deville JL, Salas S, Figarella-Branger D, Ouafik L, Daniel L. Adrenomedullin as a therapeutic target in angiogenesis. Expert Opin Ther Targets 2010;14:1059-72 . Le Retraite L, Eisinger F, Loundou A, Rinaldi Y, Seitz JF, Auquier P. Sociogeographical factors associated with participation in colorectal cancer screening. Gastroenterol Clin Biol 2010; 34:534-40. Mazouni C, Baggerly K, Hawke D, Tsavachidis S, André F, Buzdar AU, et al. Evaluation of changes in serum protein profiles during neoadjuvant chemotherapy in HER2-positive breast cancer using an LC-MALDI-TOF/MS procedure. Proteomics 2010;10:3525-32 . Lagier JC, Lepidi H, Raoult D, Fenollar F. Systemic Tropheryma whipplei: clinical presentation of 142 patients with infections diagnosed or confirmed in a reference center. Medicine (Baltimore) 2010; 89:337-45 . Bentz L, Enel P, Dunais B, Durant J, Poizot-Martin I, Tourette-Turgis C, et al. Evaluating counseling outcome on adherence to prophylaxis and follow-up after sexual HIV-risk exposure: a randomized controlled trial. AIDS Care 2010;22:1509-16. Ducray F, de Reyniès A, Chinot O, Idbaih A, Figarella-Branger D, Colin C, et al. An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients. Mol Cancer 2010;9:234. Pôle hospitalier. D.A.C.C.O.R.D. 6/22 Figarella-Branger D, Colin C, Tchoghandjian A, Baeza N, Bouvier C. Glioblastomes : oncogenèse et bases biologiques. Neurochirurgie 2010;56:441-8. Putoux A, Mougou-Zerelli S, Thomas S, Elkhartoufi N, Audollent S, Le Merrer M, et al. BBS10 mutations are common in 'Meckel'-type cystic kidneys. J Med Genet 2010;47:84852. Leydet-Quilici H, Le Corroller T, Bouvier C, Giorgi R, Argenson JN, Champsaur P, et al. Advanced hip osteoarthritis: magnetic resonance imaging aspects and histopathology correlations. Osteoarthritis Cartilage 2010;18:1429-35. Bonnetain F, Dahan L, Maillard E, Ychou M, Mitry E, Hammel P, et al. Time until definitive quality of life score deterioration as a means of longitudinal analysis for treatment trials in patients with metastatic pancreatic adenocarcinoma. Eur J Cancer 2010;46:2753-62. Dubois M, Baumstarck-Barrau K, Gaudy-Marqueste C, Richard MA, Loundou A, Auquier P, et al. Quality of life in alopecia areata: a study of 60 cases. J Invest Dermatol 2010;130:2830-3. Vitte J, Traver S, Maués De Paula A, Lesage S, Rovelli G, Corti O, et al. Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease. J Neuropathol Exp Neurol 2010; 69:959-72. Agarwala SS, di Pietro A, Flaherty KT, Garbe C, Grob JJ, Kashani-Sabet M, et al. Meeting report from the Third Global Workshop on Melanoma. Pigment Cell Melanoma Res 2010; 23:e1-7. Bataille S, Daniel L, Legris T, Vacher-Coponat H, Purgus R, Berland Y, et al. Osseous metaplasia in a kidney allograft. Nephrol Dial Transplant 2010;25:3796-8 . Fontas E, Kousignian I, Pradier C, Poizot-Martin I, Durier C, Weiss L, et al. IL-2 therapy: potential impact of the CD4 cell count at initiation on clinical efficacy--results from the ANRS CO4 cohort. J Antimicrob Chemother 2010;65:2215-23 . Rouzier C, Le Guédard-Méreuze S, Fragaki K, Serre V, Miro J, Tuffery-Giraud S, et al. The severity of phenotype linked to SUCLG1 mutations could be correlated with residual amount of SUCLG1 protein. J Med Genet 2010;47:670-6. Vidal V, Rolland PH, Daniel L, Moulin G, Bartoli JM, Levrier O. Effectiveness of endovascular embolization with a collagen-based embolic agent (Marsembol) in an animal model. J Vasc Interv Radiol 2010;21:1419-23. Gross E, Hannoun-Levi JM, Rouanet P, Houvenaeghel G, Teissier E, Ellis S, et al. Reconstruction mammaire immédiate après mastectomie suivie de radiothérapie: facteurs de risque de complications. Cancer Radiother 2010;14:704-10 . Roussel-Gervais A, Bilodeau S, Vallette S, Berthelet F, Lacroix A, Figarella-Branger D, et al. Cooperation between cyclin E and p27(Kip1) in pituitary tumorigenesis. Mol Endocrinol 2010; 24:1835-45 . Raverot G, Sturm N, de Fraipont F, Muller M, Salenave S, Caron P, et al. Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. J Clin Endocrinol Metab 2010;95:4592-9 . Carsin A, Mely L, Chrestian MA, Devred P, de Lagausie P, Guys JM, et al. Association of three different congenital malformations in a same pulmonary lobe in a 5-year-old girl. Pediatr Pulmonol 2010;45:832-5 . Pôle hospitalier. D.A.C.C.O.R.D. 7/22 Lagier JC, Fenollar F, Lepidi H, Raoult D. Failure and relapse after treatment with trimethoprim/sulfamethoxazole in classic Whipple's disease. J Antimicrob Chemother 2010; 65:2005-12. Claeys KG, Pellissier JF, Garcia-Bragado F, Weis J, Urtizberea A, Poza JJ, et al. Myopathy with hexagonally cross-linked crystalloid inclusions: delineation of a clinico-pathological entity. Neuromuscul Disord 2010;20:701-8. Uro-Soste E, Fernandez C, Authier FJ, Bassez G, Butori C, Chapon F, et al. Prise en charge des biopsies musculaires et nerveuses. Recommandations formalisées d'experts sous l'égide de la Société française de neuropathologie, de la Société française de myologie et de l'Association française contre les myopathies. Rev Neurol (Paris) 2010;166:477-85. Salmon-Céron D, Durier C, Desaint C, Cuzin L, Surenaud M, Hamouda NB, et al. Immunogenicity and safety of an HIV-1 lipopeptide vaccine in healthy adults: a phase 2 placebo-controlled ANRS trial. AIDS 2010;24:2211-23 . Coulibaly B, Sigaudy S, Girard N, Popovici C, Missirian C, Heckenroth H, et al. Coffin-Siris syndrome with multiple congenital malformations and intrauterine death: towards a better delineation of the severe end of the spectrum. Eur J Med Genet 2010;53:318-21 . Ouaissi M, Hubert C, Verhelst R, Astarci P, Sempoux C, Jouret-Mourin A, et al. Vascular reconstruction during pancreatoduodenectomy for ductal adenocarcinoma of the pancreas improves resectability but does not achieve cure. World J Surg 2010;34:2648-61 . Angelakis E, Fenollar F, Lepidi H, Birg ML, Raoult D. Tropheryma whipplei in the skin of patients with classic Whipple's disease. J Infect 2010;61:266-9 . Mazouni C, Bonnier P, Goubar A, Romain S, Martin PM. Is quantitative oestrogen receptor expression useful in the evaluation of the clinical prognosis? Analysis of a homogeneous series of 797 patients with prospective determination of the ER status using simultaneous EIA and IHC. Eur J Cancer 2010;46:2716-25. Negre T, Haddad M, Garaix F, Fernandez C, Guys JM, de Lagausie P. Laparoscopic nephrectomy of a cross-fused ectopic kidney in a child with hypertension. J Pediatr Urol 2010;6:522-4. De Paula AM, André N, Fernandez C, Coulibaly B, Scavarda D, Lena G, et al. Solitary, extracutaneous, skull-based juvenile xanthogranuloma. Pediatr Blood Cancer 2010;55:3802. Chibon F, Lagarde P, Salas S, Pérot G, Brouste V, Tirode F, et al. Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity. Nat Med 2010;16:781-7. Ouaïssi M, Cresti S, Giger U, Sielezneff I, Pirrò N, Berthet B, et al. Management of rectovaginal fistulas after prosthetic reinforcement treatment for pelvic organ prolapse. World J Gastroenterol 2010; 16:3011-5 . Mercier C, Dahan L, Ouafik L, André N, Ciccolini J. Letter to the editor: pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism. Eur J Clin Pharmacol 2010;66:959-60 . Fournier PE, Thuny F, Richet H, Lepidi H, Casalta JP, Arzouni JP, et al. Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases. Clin Infect Dis 2010;51:131-40 . Ayyadurai S, Lepidi H, Nappez C, Raoult D, Drancourt M. Lovastatin protects against experimental plague in mice. PLoS One 2010;5:e10928 . Pôle hospitalier. D.A.C.C.O.R.D. 8/22 Grob JJ, Boulinguez S. L'urticaire: actualités. Introduction. Ann Dermatol Venereol 2010; 137:18. Gaudy-Marqueste C, Roll P, Esteves-Vieira V, Weiller PJ, Grob JJ, Cau P, et al. LBR mutation and nuclear envelope defects in a patient affected with Reynolds syndrome. J Med Genet 2010;47:361-70. Grob JJ, Boulinguez S. Les recommandations dans l'urticaire. Ann Dermatol Venereol 2010; 137:19-23. Sargent DJ, Marsoni S, Monges G, Thibodeau SN, Labianca R, Hamilton SR, et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 2010;28:3219-26 . Jacopin S, Viehweger E, Glard Y, Launay F, Jouve JL, Bouvier C, et al. Fatal lung metastasis secondary to index finger giant cell tumor in an 8-year-old child. Orthop Traumatol Surg Res 2010; 96:310-3 . Metellus P, Guyotat J, Chinot O, Durand A, Barrie M, Giorgi R, et al. Adult intracranial WHO grade II ependymomas: long-term outcome and prognostic factor analysis in a series of 114 patients. Neuro Oncol 2010;12:976-84. Thouënnon E, Pierre A, Tanguy Y, Guillemot J, Manecka DL, Guérin M, et al. Expression of trophic amidated peptides and their receptors in benign and malignant pheochromocytomas: high expression of adrenomedullin RDC1 receptor and implication in tumoral cell survival. Endocr Relat Cancer 2010;17:637-51 . Salas S, Huynh T, Deville JL, Duffaud F. Antiangiogènes dans les sarcomes des tissus mous. Bull Cancer 2010;97:701-5. Jourde-Chiche N, Dussol B, Daniel L. Les atteintes rénales au cours des hémopathies malignes. Stratégie diagnostique. Rev Med Interne 2010;31:685-96 . Le Corroller T, Bouvier C, Amous Z, Champsaur P. Articular angioleiomyoma presenting as cyclic hip pain. Joint Bone Spine 2010;77:483-4. Mallet S, Boye T, Hesse S, Fournier B, Guennoc B, Carsuzaa F. Fibromatose hyaline juvénile. Ann Dermatol Venereol 2010;137:364-8. Bollée G, Martinez F, Moulin B, Meulders Q, Rougier JP, Baumelou A, et al. Renal biopsy practice in France: results of a nationwide study. Nephrol Dial Transplant 2010;25:357985. Perret-Court A, Fernandez C, Monestier S, Millet V, Tasei AM. Métastase placentaire de mélanome : un nouveau cas et revue de la littérature. Ann Pathol 2010;30:143-6. Prey S, Paul C, Bronsard V, Puzenat E, Gourraud PA, Aractingi S, et al. Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: a systematic review of the literature. J Eur Acad Dermatol Venereol 2010;24 Suppl 2:31-5 . Prey S, Paul C, Bronsard V, Puzenat E, Gourraud PA, Aractingi S, et al. Cardiovascular risk factors in patients with plaque psoriasis: a systematic review of epidemiological studies. J Eur Acad Dermatol Venereol 2010;24 Suppl 2:23-30 . Bronsard V, Paul C, Prey S, Puzenat E, Gourraud PA, Aractingi S, et al. What are the best outcome measures for assessing quality of life in plaque type psoriasis? A systematic review of the literature. J Eur Acad Dermatol Venereol 2010;24 Suppl 2:17-22 . Pôle hospitalier. D.A.C.C.O.R.D. 9/22 Puzenat E, Bronsard V, Prey S, Gourraud PA, Aractingi S, Bagot M, et al. What are the best outcome measures for assessing plaque psoriasis severity? A systematic review of the literature. J Eur Acad Dermatol Venereol 2010;24 Suppl 2:10-6 . Paul C, Gourraud PA, Bronsard V, Prey S, Puzenat E, Aractingi S, et al. Evidence-based recommendations to assess psoriasis severity: systematic literature review and expert opinion of a panel of dermatologists. J Eur Acad Dermatol Venereol 2010;24 Suppl 2:2 Chefrour M, Fischel JL, Formento P, Giacometti S, Ferri-Dessens RM, Marouani H, et al. Erlotinib in combination with capecitabine (5'dFUR) in resistant pancreatic cancer cell lines. J Chemother 2010;22:129-33 . Romeo E, Gisserot O, de Jaureguiberry JP, Desse N, Souraud JB, Salem N, et al. Meningeal chondroblastic osteosarcoma: case report and review of the literature. J Neurooncol 2010;100:305-9. Gross E, Champetier C, Pointreau Y, Zaccariotto A, Dubergé T, Guerder C, et al. Tolérance à l'irradiation des tissus sains: les ovaires. Cancer Radiother 2010;14:373-5 . Poizot-Martin I. Antagonistes du CCR5 : apport d'une nouvelle classe d'antirétroviraux dans la prise en charge de l'infection par le VIH. Med Mal Infect 2010;40:245-55 . Cowen D, Gross E, Rouannet P, Teissier E, Ellis S, Resbeut M, et al. Immediate postmastectomy breast reconstruction followed by radiotherapy: risk factors for complications. Breast Cancer Res Treat 2010;121:627-34 . Champetier C, Gross E, Pointreau Y, Zaccariotto A, Dubergé T, Guerder C, et al. Dose de tolérance à l'irradiation des tissus sains: les testicules. Cancer Radiother 2010;14:376-8. Halioua B, Richard MA, Groupe d'experts sur l'eczéma chronique des mains. Mise au point sur l'eczéma chronique des mains. Ann Dermatol Venereol 2010;137:315-27 . Levy Bencheton A, Mallet S, Rojat Habib MC, Figarella-Branger D, Sigaudy S, Grob JJ, et al. Neurofibrome plexiforme isolé de survenue tardive, en dehors d'un contexte de neurofibromatose. Ann Dermatol Venereol 2010;137:301-4 . Kluger N, Monestier S, Blatiere V. Complications related to abdominal microdermal implants during pregnancy. J Plast Reconstr Aesthet Surg 2010;63:e699-700 . Gomez-Brouchet A, Mourcin F, Gourraud PA, Bouvier C, De Pinieux G, Le Guelec S, et al. Galectin-1 is a powerful marker to distinguish chondroblastic osteosarcoma and conventional chondrosarcoma. Hum Pathol 2010;41:1220-30 . Taïeb D, Sebag F, Farman-Ara B, Portal T, Baumstarck-Barrau K, Fortanier C, et al. Iodine biokinetics and radioiodine exposure after recombinant human thyrotropin-assisted remnant ablation in comparison with thyroid hormone withdrawal. J Clin Endocrinol Metab 2010; 95:3283-90 . Fernandez C, Tatard VM, Bertrand N, Dahmane N. Differential modulation of Sonichedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Dev Neurosci 2010;32:59-70. Colson P, Richet H, Desnues C, Balique F, Moal V, Grob JJ, et al. Pepper mild mottle virus, a plant virus associated with specific immune responses, Fever, abdominal pains, and pruritus in humans. PLoS One 2010; 5:e10041 . André N, Padovani L, Verschuur A. Metronomic chemotherapy: Back to the future! Drug News Perspect 2010; 23:143-51. Pôle hospitalier. D.A.C.C.O.R.D. 10/22 Mitry E, Hammel P, Deplanque G, Mornex F, Levy P, Seitz JF, et al. Safety and activity of masitinib in combination with gemcitabine in patients with advanced pancreatic cancer. Cancer Chemother Pharmacol 2010;66:395-403. Bauchet L, Mathieu-Daudé H, Fabbro-Peray P, Rigau V, Fabbro M, Chinot O, et al. Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004. Neuro Oncol 2010;12:725-35. Lopater J, Hery G, Haddad M, Ughetto F, Gorincour G, Fernandez C, et al. Congenital pouch colon: antenatal diagnosis and video-assisted management. Pediatr Surg Int 2010;26:75961. Carpentier A, Metellus P, Ursu R, Zohar S, Lafitte F, Barrié M, et al. Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study. Neuro Oncol 2010;12:401-8. Sallée M, Daniel L, Piercecchi MD, Jaubert D, Fremeaux-Bacchi V, Berland Y, et al. Myocardial infarction is a complication of factor H-associated atypical HUS. Nephrol Dial Transplant 2010;25:2028-32. Coulibaly B, Nanni I, Quilichini B, Gaudart J, Metellus P, Fina F, et al. Epidermal growth factor receptor in glioblastomas: correlation between gene copy number and protein expression. Hum Pathol 2010;41:815-23. Cherenko M, Slotema E, Sebag F, De Micco C, Henry JF. Mild hypercalcitoninaemia and sporadic thyroid disease. Br J Surg 2010;97:684-90. Salas S, Chibon F, Noguchi T, Terrier P, Ranchere-Vince D, Lagarde P, et al. Molecular characterization by array comparative genomic hybridization and DNA sequencing of 194 desmoid tumors. Genes Chromosomes Cancer 2010;49:560-8. Amoureux MC, Coulibaly B, Chinot O, Loundou A, Metellus P, Rougon G, et al. Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines. BMC Cancer 2010;10:91. Scavarda D, Imada V, Rolland AC, Lortie A, Mercier C, Carmant L. Peri-insular hemispherotomy in children: a single institution experience. Minerva Pediatr 2010;62:1-7. Thomas PA, Payan-Defais MJ. Tumeurs épithéliales thymiques. Rev Pneumol Clin 2010; 66:41-51. Moreau E, André N, Coze C, Padovani L, Mercier C, Ciccolini J. Can CDA deficiency explain tumour lysis syndrome in a child with neuroblastoma receiving gemcitabine? Pediatr Blood Cancer 2010; 54:781-2. Lin EY, Tsigrelis C, Baddour LM, Lepidi H, Rolain JM, Patel R, et al. Candidatus Bartonella mayotimonensis and endocarditis. Emerg Infect Dis 2010;16:500-3 . El Ayachi I, Baeza N, Fernandez C, Colin C, Scavarda D, Pesheva P, et al. KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas. Neuropathol Appl Neurobiol 2010;36:399-410 . Dômont J, Salas S, Lacroix L, Brouste V, Saulnier P, Terrier P, et al. High frequency of beta-catenin heterozygous mutations in extra-abdominal fibromatosis: a potential molecular tool for disease management. Br J Cancer 2010;102:1032-6 . Harhouri K, Kebir A, Guillet B, Foucault-Bertaud A, Voytenko S, Piercecchi-Marti MD, et al. Soluble CD146 displays angiogenic properties and promotes neovascularization in experimental hind-limb ischemia. Blood 2010;115:3843-51. Pôle hospitalier. D.A.C.C.O.R.D. 11/22 Rosmorduc O, Chevreau C, Dielenseger P, Ederhy S, Goldwasser F, Grange JD, et al. Bon usage du sorafénib chez les patients pris en charge pour un carcinome hépatocellulaire ou un cancer du rein. Gastroenterol Clin Biol 2010;34:161-7 . Raverot G, Wierinckx A, Dantony E, Auger C, Chapas G, Villeneuve L, et al. Prognostic factors in prolactin pituitary tumors: clinical, histological, and molecular data from a series of 94 patients with a long postoperative follow-up. J Clin Endocrinol Metab 2010;95:170816. Pirro N, Le Corroller T, Lagier A, Ouaissi M, Sielezneff I, Pignodel C, et al. Le ganglion de Mondor : mythe ou réalité ? Morphologie 2010;94:9-12. Taïeb D, Giusiano S, Sebag F, Marcy M, de Micco C, Palazzo FF, et al. Tumor protein p53induced nuclear protein (TP53INP1) expression in medullary thyroid carcinoma: a molecular guide to the optimal extent of surgery? World J Surg 2010;34:830-5. Benoit M, Thuny F, Le Priol Y, Lepidi H, Bastonero S, Casalta JP, et al. The transcriptional programme of human heart valves reveals the natural history of infective endocarditis. PLoS One 2010;5:e8939 . Duflo S, Mahieu-Renard L, Gras R, Grob JJ, Zanaret M. Valeurs cinetiques de la lymphoscintigraphie du ganglion sentinelle dans les melanomes malins cutanes cervicofaciaux. J Otolaryngol Head Neck Surg 2010;39:39-44. Faivre A, Franques J, De Paula AM, Gutierrez M, Bret S, Aubert S, et al. Acute motor and sensory axonal neuropathy and concomitant encephalopathy during tumor necrosis factoralpha antagonist therapy. J Neurol Sci 2010;291:103-6. Marie D, Dany L, Cannone P, Dudoit E, Duffaud F. Représentations sociales du cancer et de la chimiothérapie: enjeux pour la définition de la situation thérapeutique. Bull Cancer 2010;97:577-87. Laigle-Donadey F, Figarella-Branger D, Chinot O, Taillandier L, Cartalat-Carel S, Honnorat J, et al. Up-front temozolomide in elderly patients with glioblastoma. J Neurooncol 2010; 99:89-94. Chabannon C, Honstettre A, Daufresne LM, Martin PM, Bonnetaud C, Birtwisle-Peyrottes I, et al. La publication de catalogues de collections d'échantillons biologiques par les tumorothèques. Bull Cancer 2010;97:181-9. Cowen D, Bedingfield P, McConkey GA, Fishwick CW, Johnson AP. A study of the effects of substituents on the selectivity of the binding of N-arylaminomethylene malonate inhibitors to DHODH. Bioorg Med Chem Lett 2010;20:1284-7 . Raynal C, Ciccolini J, Mercier C, Boyer JC, Polge A, Lallemant B, et al. High-resolution melting analysis of sequence variations in the cytidine deaminase gene (CDA) in patients with cancer treated with gemcitabine. Ther Drug Monit 2010; 32:53-60. Wolchok JD, Neyns B, Linette G, Negrier S, Lutzky J, Thomas L, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010;11:155-64. Michel L, Villes V, Dabis F, Spire B, Winnock M, Loko MA, et al. Role of treatment for depressive symptoms in relieving the impact of fatigue in HIV-HCV co-infected patients: ANRS Co13 Hepavih, France, 2006-2008. J Viral Hepat 2010;17:650-60. Borentain P, Colson P, Coso D, Bories E, Charbonnier A, Stoppa AM, et al. Clinical and virological factors associated with hepatitis B virus reactivation in HBsAg-negative and antiHBc antibodies-positive patients undergoing chemotherapy and/or autologous stem cell transplantation for cancer. J Viral Hepat 2010;17:807-15 . Pôle hospitalier. D.A.C.C.O.R.D. 12/22 Spinelli V, Chinot O, Cabaniols C, Giorgi R, Alla P, Lehucher-Michel MP. Occupational and environmental risk factors for brain cancer: a pilot case-control study in France. Presse Med 2010; 39:e35-44. Garbe C, Peris K, Hauschild A, Saiag P, Middleton M, Spatz A, et al. Diagnosis and treatment of melanoma: European consensus-based interdisciplinary guideline. Eur J Cancer 2010;46:270-83. Barat-Houari M, Nguyen K, Bernard R, Fernandez C, Vovan C, Bareil C, et al. New multiplex PCR-based protocol allowing indirect diagnosis of FSHD on single cells: can PGD be offered despite high risk of recombination? Eur J Hum Genet 2010;18:533-8 . Ciccolini J, Dahan L, André N, Evrard A, Duluc M, Blesius A, et al. Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies. J Clin Oncol 2010;28:160-5. Coulibaly B, Piercecchi-Marti MD, Bartoli C, Liprandi A, Léonetti G, Pellissier JF. Lethal injection of potassium chloride: first description of the pathological appearance of organs. J Appl Toxicol 2010;30:378-80 . Tessonnier L, Sebag F, Ghander C, De Micco C, Reynaud R, Palazzo FF, et al. Limited value of 18F-F-DOPA PET to localize pancreatic insulin-secreting tumors in adults with hyperinsulinemic hypoglycemia. J Clin Endocrinol Metab 2010; 95:303-7. Thuny F, Fournier PE, Casalta JP, Gouriet F, Lepidi H, Riberi A, et al. Investigation of blood culture-negative early prosthetic valve endocarditis reveals high prevalence of fungi. Heart 2010;96:743-7. Penel N, Italiano A, Isambert N, Bompas E, Bousquet G, Duffaud F, et al. Factors affecting the outcome of patients with metastatic leiomyosarcoma treated with doxorubicincontaining chemotherapy. Ann Oncol 2010;21:1361-5 . Piercecchi-Marti MD, De Paula AM, Gavaudan G, Bartoli C, Pelissier-Alicot AL, Leonetti G, et al. Interpretation of neuropathological lesions: its limitations in medico-legal experts' reports. Forensic Sci Int 2010;194:e1-3 . Wein N, Krahn M, Courrier S, Bartoli M, Salort-Campana E, Nguyen K, et al. Immunolabelling and flow cytometry as new tools to explore dysferlinopathies. Neuromuscul Disord 2010; 20:57-60. Lagier JC, Fenollar F, Lepidi H, Liozon E, Raoult D. Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide. J Infect 2010; 60:79-82. Fernandez C, Halbert C, De Paula AM, Lacroze V, Froissart R, Figarella-Branger D, et al. Non-lethal neonatal neuromuscular variant of glycogenosis type IV with novel GBE1 mutations. Muscle Nerve 2010;41:269-71 . Naldi L, Svensson A, Zenoni D, Diepgen T, Elsner P, Grob JJ, et al. Comparators, study duration, outcome measures and sponsorship in therapeutic trials of psoriasis: update of the EDEN Psoriasis Survey 2001-2006. Br J Dermatol 2010;162:384-9 . Vincentelli F, Caruso G, Figarella-Branger D. Primary intradural Ewing's sarcoma of the cauda equina presenting with acute bleeding. Acta Neurochir (Wien) 2010;152:563-4. Lah TT, Nanni I, Trinkaus M, Metellus P, Dussert C, De Ridder L, et al. Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. J Neurosurg 2010;112:940-50 . Deville JL, Gravis G, Salem N, Savoie PH, Esterni B, Walz J, et al. Resection of residual masses after chemotherapy for advanced non-seminomatous germ cell tumours, a Pôle hospitalier. D.A.C.C.O.R.D. 13/22 monocentric analysis of pre-operative prognosticators. Eur J Cancer Care (Engl) 2010;19:827-32. Thuny C, Gaudy-Marqueste C, Nicol I, Gabert J, Costello R, Grob JJ, et al. Chronic eosinophilic leukaemia revealed by lymphomatoid papulosis: the role of the FIP1-like 1platelet-derived growth factor receptor alpha fusion gene. J Eur Acad Dermatol Venereol 2010;24:234-5. El Khloufi S, Rhissassi B, Bjijou Y, Bouchikhi M, Jiddane M, Bensouda M, et al. Eviscération spontanée transvaginale de l'intestin grêle. Presse Med 2010;39:513-5. Mohty AM, Grob JJ, Mohty M, Richard MA, Olive D, Gaugler B. Induction of IP-10/CXCL10 secretion as an immunomodulatory effect of low-dose adjuvant interferon-alpha during treatment of melanoma. Immunobiology 2010;215:113-23. Tchoghandjian A, Baeza N, Colin C, Cayre M, Metellus P, Beclin C, et al. A2B5 cells from human glioblastoma have cancer stem cell properties. Brain Pathol 2010;20:211-21 . ANNÉE 2011 Irani Y, Pype JL, Martin AR, Chong CF, Daniel L, Gaudart J, et al. Noble gas (argon and xenon)-saturated cold storage solutions reduce ischemia-reperfusion injury in a rat model of renal transplantation. Nephron Extra 2011;1:272-82 . Rahim M, Bellemare ME, Pirró N, Bulot R. Automatic estimation of pelvic organ anatomical references. Conf Proc IEEE Eng Med Biol Soc 2011;2011:5124-7. Gomez-Brouchet A, Bouvier C, Decouvelaere AV, Larousserie F, Aubert S, Leroy X, et al. Rôle du pathologiste dans la prise en charge des tumeurs osseuses primitives malignes : ostéosarcomes et tumeurs de la famille Ewing après traitement néoadjuvant. Ann Pathol 2011; 31:455-65. André N, Abed S, Orbach D, Alla CA, Padovani L, Pasquier E, et al. Pilot study of a pediatric metronomic 4-drug regimen. Oncotarget 2011;2:960-5 . Richard MA. Psoriasis : 2011;138:813-20. bilan préthérapeutique pratique. Ann Dermatol Venereol Dahan L, Norguet E, Etienne-Grimaldi MC, Formento JL, Gasmi M, Nanni I, et al. Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer. BMC Cancer 2011;11:496 . Lok C, Mouthon L, Ségard M, Richard MA, Guillevin L. Les ulcères digitaux de la sclérodermie systémique. Ann Dermatol Venereol 2011;138:762-8; quiz 761, 769 . Bonerandi JJ, Beauvillain C, Caquant L, Chassagne JF, Chaussade V, Clavère P, et al. Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma and precursor lesions. J Eur Acad Dermatol Venereol 2011;25 Suppl 5:1-51 . Padovani L, Andre N, Gentet JC, Figarella Branger D, Scavarda D, Verschuur A, et al. Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease? J Pediatr Hematol Oncol 2011;33:600-4 . Duval-Sabatier A, Gondouin B, Bouvier C, Bataille S, Berland Y, Brunet P. Brown tumor: still an old disease? Kidney Int 2011;80:1110. Pôle hospitalier. D.A.C.C.O.R.D. 14/22 Negre T, Faure A, Andre M, Daniel L, Coulange C, Lechevallier E. Angiomyolipomes rénaux sans composante graisseuse : caractéristiques tomodensitométriques, histologiques et évolutives. Prog Urol 2011;21:837-41. Cuisset T, Fernandez C, Jolibert M, Unal C, Quilici J. Acute coronary syndrome due to extrinsic compression of the left coronary system by metastatic liposarcoma successful treatment with percutaneous coronary intervention. J Am Coll Cardiol 2011;58:2014. Deville JL. Chimiothérapie en oncologie urologique. Prog Urol 2011;21:816-21. Gross E. Radiothérapie conformationelle du cancer de prostate. Prog Urol 2011;21:801-7. Bertolotto C, Lesueur F, Giuliano S, Strub T, de Lichy M, Bille K, et al. A SUMOylationdefective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature 2011; 480:94-8 . Fourcade S, Gaudy-Marqueste C, Tasei AM, Richard MA, Grob JJ. Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy. Arch Dermatol 2011;147:1227-8 . Padovani L, André N, Gentet JC, Muracciole X. Medulloblastoma. Eur J Cancer 2011;47 Suppl 3:S338. Figarella-Branger D, Maues de Paula A, Colin C, Bouvier C. Histomolecular classification of adult diffuse gliomas: the diagnostic value of immunohistochemical markers. Rev Neurol (Paris) 2011; 167:683-90 . Brégeon F, Xeridat F, Andreotti N, Lepidi H, Delpierre S, Roch A, et al. Activation of nicotinic cholinergic receptors prevents ventilator-induced lung injury in rats. PLoS One 2011; 6:e22386 . Salas S, Dufresne A, Bui B, Blay JY, Terrier P, Ranchere-Vince D, et al. Prognostic factors influencing progression-free survival determined from a series of sporadic desmoid tumors: a wait-and-see policy according to tumor presentation. J Clin Oncol 2011;29:3553-8 . Kaba M, Richet H, Ravaux I, Moreau J, Poizot-Martin I, Motte A, et al. Hepatitis E virus infection in patients infected with the human immunodeficiency virus. J Med Virol 2011;83:1704-16. Javelle E, Gasperini G, Mercier J, Luciano L, Sagui E, Soulier M, et al. A 78-year-old woman with an acute eosinophilic gastroenteritis. Clin Res Hepatol Gastroenterol 2011;35:755-8. Acunzo J, Roche C, Defilles C, Thirion S, Quentien MH, Figarella-Branger D, et al. Inactivation of PITX2 transcription factor induced apoptosis of gonadotroph tumoral cells. Endocrinology 2011;152:3884-92. Du-Thanh A, Merlet S, Maillard H, Bernard P, Joly P, Estève E, et al. Combined treatment with low-dose methotrexate and initial short-term superpotent topical steroids in bullous pemphigoid: an open, multicentre, retrospective study. Br J Dermatol 2011;165:1337-43. Norguet E, Dahan L, Gaudart J, Gasmi M, Ouafik L, Seitz JF. Cetuximab after bevacizumab in metastatic colorectal cancer: is it the best sequence? Dig Liver Dis 2011;43:917-9 . Padovani L, Regis JM, Muracciole X. Breast cancer--what about radiosurgery for brain metastasis? Nat Rev Clin Oncol 2011;8:506; author reply 506 . Pôle hospitalier. D.A.C.C.O.R.D. 15/22 Lehtokari VL, Pelin K, Herczegfalvi A, Karcagi V, Pouget J, Franques J, et al. Nemaline myopathy caused by mutations in the nebulin gene may present as a distal myopathy. Neuromuscul Disord 2011;21:556-62 . Gállego Pérez-Larraya J, Ducray F, Chinot O, Catry-Thomas I, Taillandier L, Guillamo JS, et al. Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. J Clin Oncol 2011;29:3050-5 . Grob JJ. La prolifération des recommandations pour la pratique améliore-t-elle les soins aux patients ? Ann Dermatol Venereol 2011;138:465-6 . Fenollar F, Nicoli F, Paquet C, Lepidi H, Cozzone P, Antoine JC, et al. Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis. BMC Infect Dis 2011;11:171 Le Corroller T, Lagier A, Pirro N, Champsaur P. Anatomical study of the infrapatellar branch of the saphenous nerve using ultrasonography. Muscle Nerve 2011;44:50-4 . Metellus P, Colin C, Taieb D, Guedj E, Nanni-Metellus I, de Paula AM, et al. IDH mutation status impact on in vivo hypoxia biomarkers expression: new insights from a clinical, nuclear imaging and immunohistochemical study in 33 glioma patients. J Neurooncol 2011;105:591-600. Robert C, Thomas L, Bondarenko I, O'Day S, M D JW, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011;364:251726. Gabriel S, Farman-Ara B, Bourrelly M, Carpentier O, Sebag F, Palazzo FF, et al. Radiation doses to cohabitants of patients undergoing radioiodine ablation for thyroid cancer: poor compliance with radiation protection guidelines but low radiation exposure. Nucl Med Commun 2011;32:829-33 . Ugnon-Café S, Dorey A, Bilheude JM, Streichenberger N, Viennet G, Meyronet D, et al. Rapid screening and confirmatory methods for biochemical diagnosis of human prion disease. J Virol Methods 2011;175:216-23 . Coulibaly B, Piercecchi-Marti MD, Fernandez C, Wasier AP, Viard L, Fraisse A, et al. Une cause rare de défaillance cardiaque brutale chez le nourrisson : la cardiomyopathie histiocytoïde. Ann Pathol 2011;31:93-7 . Taïeb D, Baumstarck-Barrau K, Sebag F, Fortanier C, De Micco C, Loundou A, et al. Heathrelated quality of life in thyroid cancer patients following radioiodine ablation. Health Qual Life Outcomes 2011;9:33. Flandre P, Pugliese P, Cuzin L, Bagnis CI, Tack I, Cabié A, et al. Risk factors of chronic kidney disease in HIV-infected patients. Clin J Am Soc Nephrol 2011;6:1700-7. Rigau V, Zouaoui S, Mathieu-Daudé H, Darlix A, Maran A, Trétarre B, et al. French brain tumor database: 5-year histological results on 25 756 cases. Brain Pathol 2011;21:633-44. Cordier PY, Nau A, Ciccolini J, Oliver M, Mercier C, Lacarelle B, et al. 5-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases. Cancer Chemother Pharmacol 2011;68:823-6 . Lanoy E, Rosenberg PS, Fily F, Lascaux AS, Martinez V, Partisani M, et al. HIV-associated Hodgkin lymphoma during the first months on combination antiretroviral therapy. Blood 2011;118:44-9. Mazouni C, Bonnier P, Romain S, Martin PM. A nomogram predicting the probability of primary breast cancer survival at 2- and 5-years using pathological and biological tumor parameters. J Surg Oncol 2011;103:746-50 . Pôle hospitalier. D.A.C.C.O.R.D. 16/22 Fournier PE, Thuny F, Grisoli D, Lepidi H, Vitte J, Casalta JP, et al. A deadly aversion to pork. Lancet 2011;377:1542 . Taillandier L, Blonski M, Carrie C, Bernier V, Bonnetain F, Bourdeaut F, et al. Les médulloblastomes: revue générale. Rev Neurol (Paris) 2011;167:431-48 . Faure A, Negre T, Murraciole X, Jouve E, Sambuc R, Cowen D, et al. La radiothérapie conformationnelle associée à l'hormonothérapie du cancer de prostate localisé: l'âge est-il un facteur limitant ? Prog Urol 2011;21:333-40 . Makinson A, Tenon JC, Eymard-Duvernay S, Pujol JL, Allavena C, Cuzin L, et al. Human immunodeficiency virus infection and non-small cell lung cancer: survival and toxicity of antineoplastic chemotherapy in a cohort study. J Thorac Oncol 2011;6:1022-9 . Levy-Roy A, Tasei AM, Richard MA. Quel est votre diagnostic ? Elastolyse du derme moyen. Ann Dermatol Venereol 2011;138:324-6 . Mapoure NY, Ali-Ahmad R, Aubert L, Fernandez C, Schleinitz N, Macia F. Polyneuropathie axonale aiguë et syndrome de Gougerot-Sjögren. Rev Neurol (Paris) 2011;167:530-2. Metellus P, Nanni-Metellus I, Delfino C, Colin C, Tchogandjian A, Coulibaly B, et al. Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution. Ann Surg Oncol 2011;18:2937-45 . Leroi AM, Lenne X, Dervaux B, Chartier-Kastler E, Mauroy B, Normand LL, et al. Outcome and cost analysis of sacral nerve modulation for treating urinary and/or fecal incontinence. Ann Surg 2011;253:720-32 . Metellus P, Voutsinos-Porche B, Nanni-Metellus I, Colin C, Fina F, Berenguer C, et al. Adrenomedullin expression and regulation in human glioblastoma, cultured human glioblastoma cell lines and pilocytic astrocytoma. Eur J Cancer 2011;47:1727-35. El Ayachi I, Fernandez C, Baeza N, De Paula AM, Pesheva P, Figarella-Branger D. Spatiotemporal distribution of tenascin-R in the developing human cerebral cortex parallels neuronal migration. J Comp Neurol 2011;519:2379-89 . Le Corroller T, Dediu M, Pauly V, Pirro N, Chabrand P, Champsaur P. The femoral calcar: a computed tomography anatomical study. Clin Anat 2011;24:886-92. Khosrotehrani K, Nguyen Huu S, Prignon A, Avril MF, Boitier F, Oster M, et al. Pregnancy promotes melanoma metastasis through enhanced lymphangiogenesis. Am J Pathol 2011;178:1870-80. Chinot OL, de La Motte Rouge T, Moore N, Zeaiter A, Das A, Phillips H, et al. AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme. Adv Ther 2011;28:334-40 . André N, Padovani L, Pasquier E. Metronomic scheduling of anticancer treatment: the next generation of multitarget therapy? Future Oncol 2011; 7:385-94 . Lagier JC, Fenollar F, Lepidi H, Raoult D. Evidence of lifetime susceptibility to Tropheryma whipplei in patients with Whipple's disease. J Antimicrob Chemother 2011;66:1188-9 . Sbidian E, Maza A, Montaudié H, Gallini A, Aractingi S, Aubin F, et al. Efficacy and safety of oral retinoids in different psoriasis subtypes: a systematic literature review. J Eur Acad Dermatol Venereol 2011; 25 Suppl 2:28-33 . Pôle hospitalier. D.A.C.C.O.R.D. 17/22 Maza A, Montaudié H, Sbidian E, Gallini A, Aractingi S, Aubin F, et al. Oral cyclosporin in psoriasis: a systematic review on treatment modalities, risk of kidney toxicity and evidence for use in non-plaque psoriasis. J Eur Acad Dermatol Venereol 2011;25 Suppl 2:19-27. Montaudié H, Sbidian E, Paul C, Maza A, Gallini A, Aractingi S, et al. Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity. J Eur Acad Dermatol Venereol 2011;25 Suppl 2:12-8 . Paul C, Gallini A, Maza A, Montaudié H, Sbidian E, Aractingi S, et al. Evidence-based recommendations on conventional systemic treatments in psoriasis: systematic review and expert opinion of a panel of dermatologists. J Eur Acad Dermatol Venereol 2011;25 Suppl 2:2-11. Baiardini I, Braido F, Bindslev-Jensen C, Bousquet PJ, Brzoza Z, Canonica GW, et al. Recommendations for assessing patient-reported outcomes and health-related quality of life in patients with urticaria: a GA(2) LEN taskforce position paper. Allergy 2011;66:840-4. Pessaux P, Sauvanet A, Mariette C, Paye F, Muscari F, Cunha AS, et al. External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trial. Ann Surg 2011;253:879-85. Coulibaly B, Bouvier C, Paula AM, Fernandez C, Dufour H, Figarella-Branger D. Un mélanocytome mimant un adénome hypophysaire. Ann Pathol 2011;31:50-2. Régis J, Tamura M, Park MC, McGonigal A, Rivière D, Coulon O, et al. Subclinical abnormal gyration pattern, a potential anatomic marker of epileptogenic zone in patients with magnetic resonance imaging-negative frontal lobe epilepsy. Neurosurgery 2011;69:80-93; discussion 93-4 . Dujardin F, Binh MB, Bouvier C, Gomez-Brouchet A, Larousserie F, Muret Ad, et al. MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone. Mod Pathol 2011 ; 24:624-37. Saveanu A, Muresan M, De Micco C, Taieb D, Germanetti AL, Sebag F, et al. Expression of somatostatin receptors, dopamine D? receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas. Endocr Relat Cancer 2011; 18:287-300 . Raymond E, Dahan L, Raoul JL, Bang YJ, Borbath I, Lombard-Bohas C, et al. Sunitinib malate for the treatment of pancreatic neuroendocrine tumors. N Engl J Med 2011;364:501-13. Ciccolini J, Mercier C, Dahan L, André N. Integrating pharmacogenetics into gemcitabine dosing--time for a change? Nat Rev Clin Oncol 2011;8:439-44 . Taieb G, Wacongne A, Renard D, Figarella-Branger D, Castelnovo G, Labauge P. A new case of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids with initial normal magnetic resonance imaging. Brain 2011;134:e182; author reply e183 . Lamy PJ, Fina F, Bascoul-Mollevi C, Laberenne AC, Martin PM, Ouafik L, et al. Quantification and clinical relevance of gene amplification at chromosome 17q12-q21 in human epidermal growth factor receptor 2-amplified breast cancers. Breast Cancer Res 2011;13:R15 . Bruneu-Avierinos Y, Monestier S, Tasei AM, Gaudy-Marqueste C, Grob JJ, Richard MA. Granulomes induits par des injections de leuproréline acétate (Enantone ®). Ann Dermatol Venereol 2011;138:35-7. Pôle hospitalier. D.A.C.C.O.R.D. 18/22 Ouaïssi M, Giger U, Sielezneff I, Yawovi KA, Pamela A, Pirro N, et al. Mucosal advancement flap anoplasty for chronic anal fissure resistant to conservative therapy. World J Surg 2011;35:900-4. Mazouni C, Romain S, Bonnier P, Ouafik L, Martin PM. Prognostic significance of tumorrelated proteases as a function of the estrogen receptor status. Cancer Biol Ther 2011;11:277-83. Fellah S, Girard N, Chinot O, Cozzone PJ, Callot V. Early evaluation of tumoral response to antiangiogenic therapy by arterial spin labeling perfusion magnetic resonance imaging and susceptibility weighted imaging in a patient with recurrent glioblastoma receiving bevacizumab. J Clin Oncol 2011;29:e308-11 . Rjeibi I, Mabrouk K, Mosrati H, Berenguer C, Mejdoub H, Villard C, et al. Purification, synthesis and characterization of AaCtx, the first chlorotoxin-like peptide from Androctonus australis scorpion venom. Peptides 2011;32:656-63. Sakr L, Palaniappan R, Payan MJ, Doddoli C, Dutau H. Tracheal glomus tumor: a multidisciplinary approach to management. Respir Care 2011;56:342-6. Giger U, Ouaissi M, Schmitz SF, Krähenbühl S, Krähenbühl L. Bile duct injury and use of cholangiography during laparoscopic cholecystectomy. Br J Surg 2011;98:391-6 . Lanoy E, Guiguet M, Bentata M, Rouveix E, Dhiver C, Poizot-Martin I, et al. Survival after neuroAIDS: association with antiretroviral CNS Penetration-Effectiveness score. Neurology 2011;76:644-51. Gosselin A, Bosdure E, Hesse S, Barlogis V, Chrestian MA, Dubus JC. Tuméfactions multiples chez un nouveau-né révélant une botryomycose. Arch Pediatr 2011; 18:183-5. Netsch C, Bach T, Gross E, Gross AJ. Rectourethral fistula after high-intensity focused ultrasound therapy for prostate cancer and its surgical management. Urology 2011;77:999-1004. Bourdeaut F, Lequin D, Brugières L, Reynaud S, Dufour C, Doz F, et al. Frequent hSNF5/INI1 germline mutations in patients with rhabdoid tumor. Clin Cancer Res 2011;17:31-8. Lanoy E, Spano JP, Bonnet F, Guiguet M, Boué F, Cadranel J, et al. The spectrum of malignancies in HIV-infected patients in 2006 in France: the ONCOVIH study. Int J Cancer 2011;129:467-75. Gaudy-Marqueste C, Dubois M, Richard MA, Bonnelye G, Grob JJ. Cognitive training with photographs as a new concept in an education campaign for self-detection of melanoma: a pilot study in the community. J Eur Acad Dermatol Venereol 2011;25:1099-103 . Mazouni C, Fina F, Romain S, Ouafik L, Bonnier P, Brandone JM, et al. Epstein-Barr virus as a marker of biological aggressiveness in breast cancer. Br J Cancer 2011;104:332-7 . Omuro A, Taillandier L, Chinot O, Sierra Del Rio M, Carnin C, Barrie M, et al. Primary CNS lymphoma in patients younger than 60: can whole-brain radiotherapy be deferred? J Neurooncol 2011;104:323-30 . Gaudy-Marqueste C, Perchenet AS, Taséi AM, Madjlessi N, Magalon G, Richard MA, et al. The "spaghetti technique": an alternative to Mohs surgery or staged surgery for problematic lentiginous melanoma (lentigo maligna and acral lentiginous melanoma). J Am Acad Dermatol 2011; 64:113-8 . Tournoux-Facon C, Paoletti X, Barbare JC, Bouché O, Rougier P, Dahan L, et al. Development and validation of a new prognostic score of death for patients with hepatocellular carcinoma in palliative setting. J Hepatol 2011;54:108-14. Pôle hospitalier. D.A.C.C.O.R.D. 19/22 Charrier N, Deveze A, Fakhry N, Sebag F, Morange I, Gaborit B, et al. Comparison of [¹¹¹In]pentetreotide-SPECT and [¹?F]FDOPA-PET in the localization of extra-adrenal paragangliomas: the case for a patient-tailored use of nuclear imaging modalities. Clin Endocrinol (Oxf) 2011;74:21-9. Gallien S, Journot V, Rozenbaum W, Yéni P, Morlat P, Poizot-Martin I, et al. Four year follow-up of simplification therapy with once-daily emtricitabine, didanosine and efavirenz in HIV-infected patients (ALIZE ANRS 099 trial). J Antimicrob Chemother 2011;66:184-91 . Ouaïssi M, Giger U, Sielezneff I, Pirrò N, Sastre B, Ouaissi A. Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer. J Biomed Biotechnol 2011; 2011:315939 . Bastuji-Garin S, Joly P, Lemordant P, Sparsa A, Bedane C, Delaporte E, et al. Risk factors for bullous pemphigoid in the elderly: a prospective case-control study. J Invest Dermatol 2011; 131:637-43 . Cabaniols C, Giorgi R, Chinot O, Ferahta N, Spinelli V, Alla P, et al. Links between private habits, psychological stress and brain cancer: a case-control pilot study in France. J Neurooncol 2011; 103:307-16 . Mancini J, Baumstarck-Barrau K, Simeoni MC, Grob JJ, Michel G, Tarpin C, et al. Quality of life in a heterogeneous sample of caregivers of cancer patients: an in-depth interview study. Eur J Cancer Care (Engl) 2011; 20:483-92. Le Corroller T, Wittenberg R, Pauly V, Pirro N, Champsaur P, Choquet O. A new lateral approach to the parasacral sciatic nerve block: an anatomical study. Surg Radiol Anat 2011;33:91-5. Champetier C, Hannoun-Levi JM, Resbeut M, Azria D, Salem N, Tessier E, et al. Radiothérapie postopératoire dans les sarcomes utérins: étude rétrospective multicentrique. Cancer Radiother 2011;15:89-96 . Penel N, Le Cesne A, Bui BN, Perol D, Brain EG, Ray-Coquard I, et al. Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC/French Sarcoma Group phase II trial with a long-term follow-up. Ann Oncol 2011;22:452-7 . Hannoun-Levi JM, Ortholan C, Resbeut M, Teissier E, Ronchin P, Cowen D, et al. High-dose split-course radiation therapy for anal cancer: outcome analysis regarding the boost strategy (CORS-03 study). Int J Radiat Oncol Biol Phys 2011;80:712-20 . Claeys A, Gaudy-Marqueste C, Pauly V, Pelletier F, Truchetet F, Boye T, et al. Management of pain associated with debridement of leg ulcers: a randomized, multicentre, pilot study comparing nitrous oxide-oxygen mixture inhalation and lidocaïne-prilocaïne cream. J Eur Acad Dermatol Venereol 2011; 25:138-44. Colson P, Dhiver C, Poizot-Martin I, Tamalet C, Gérolami R. Acute and chronic hepatitis E in patients infected with human immunodeficiency virus. J Viral Hepat 2011;18:227-8. Gallas S, Michot F, Faucheron JL, Meurette G, Lehur PA, Barth X, et al. Predictive factors for successful sacral nerve stimulation in the treatment of faecal incontinence: results of trial stimulation in 200 patients. Colorectal Dis 2011;13:689-96. Yang CG, Ciccolini J, Blesius A, Dahan L, Bagarry-Liegey D, Brunet C, et al. DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity. Cancer Chemother Pharmacol 2011;67:49-56. Ouaïssi M, Maggiori L, Alves A, Giger U, Sielezneff I, Valleur P, et al. Colorectal cancer complicating inflammatory bowel disease: a comparative study of Crohn's disease vs ulcerative colitis in 34 patients. Colorectal Dis 2011;13:684-8 . Pôle hospitalier. D.A.C.C.O.R.D. 20/22 Ninove L, Daniel L, Gallou J, Cougard PA, Charpentier A, Viard L, et al. Fatal case of Reye's syndrome associated with H3N2 influenza virus infection and salicylate intake in a 12-yearold patient. Clin Microbiol Infect 2011; 17:95-7 . Salas S, Huynh TK, Giorgi R, Deville JL, Bollini G, Curvale G, et al. A study of 28 flat bone osteosarcomas: prognostic factors and early and long-term outcome. Eur J Cancer Care (Engl) 2011; 20:322-9. CONTRATS ANNÉES 2010 et 2011 Neuro-oncologie Pr O.Chinot Responsable Titre D Figarella Réseau national de reference des Oligodendrogliomes O.Chinot anaplasiques (POLA) Coordinateur principal : Pr JY Delattre O. Chinot National observatory of avastin. O.Chinot PlGF as a new target in pre-clinical model D.Laffite MALDI imaging in glioma: target characterization for O.Chinot therapeutic purpose D.Laffite MALDI imaging in glioma: target characterization for O.Chinot therapeutic purpose O.Chinot Réseau national de reference des Lymphomes occulocérébraux (LOC) Coordinateurs nationaux : K.Hoang-Xuan et C.Soussain E.Tabouret Molecular angiogenesis pattern of glioblastoma from O.Chinot diagnosis to reccurence O.Chinot Clinical data base of glioma Organisme INCa Date 2009 ROCHE Hoffman la Roche ARC 2010 2010 2010 Fondation Universitaire INCa 2010 2010 FRM 2011 ARTC Sud 2011 Anatomopathologie Pr D.Figarella-Branger Responsable D.FigarellaBranger D.FigarellaBranger C. Bouvier C. Bouvier Titre Influence of the micro-environment on the growth of glioblastomas and implementation of preclinical models Study of the role of the microenvironment in the development of glioblastomas Programme carte d’identité des tumeurs : tumeurs cartilagineuses Chimiorésistance et adhérence cellulaire analysée dans un nouveau modèle d’ostéosarcome murin Organisme GEFLUC Date 2010 ANOCEF/SERVIER 2010 Ligue INCa 2010 INCa 2010 Oncologie digestive Pr JF.Seitz Responsable Titre L.Dahan FFCD 1004 : Pharmacogenetique de la gemcitabine : Etude de l’impact du polymorphisme génétique de la cytidine deaminase (cda) sur la toxicité dans les adénocarcinomes pancréatiques réséqués JF.Seitz Therapeutic drug monotoring of bevacizumab in metastatic colorectal cancer patients : search for predictive values of response Organisme date FFCD/ 2011 VALOR PACA PHRC En attente de réponse Oncologie médicale Pr F.Duffaud Responsable Titre Organisme S.Salas Conformité aux recommandations européennes concernant la prise en AORC junior charge nutritionnelle des patients cancéreux bénéficiant d’un traitement par chimiothérapie : impact sur l’état nutritionnel et la qualité de vie Pôle hospitalier. D.A.C.C.O.R.D. date 2011 21/22 THESES de DOCTORAT ANNÉES 2010 et 2011 Discipline Anatomopathologie D.Figarella-Branger Nom, Prénom Coulibaly Bema Oncologie digestive JF.Seitz Dahan Laeticia Oncologie médicale F.Duffaud Deville Jean Laurent Titre Caractérisation moléculaire et détermination de marqueurs de chimiosensibilité dans les gliomes. Facteurs prédictifs de réponse au cetuximab: modulation redox et pharmacogénétique . Thèse 2009 Expression et rôle de l'adrénomédulline dans le carcinome rénal à cellules conventionnelles. Thèse 16/12/2011 Date 2009 Pôle hospitalier. D.A.C.C.O.R.D. Directeur D.Figarella-Branger H.Kovacic L.Daniel 22/22
