!"#$%"&$'%()*()+(,(&'-.()(&)/012'$!$+'()#"3&(%'(,,()
*456789:9;8)<9)#=>?>@=9)A>?4BC?6=79)
D6BC?84)<9E)2B=9;B9E)
36:5CE)#=>567FG)+>EE9?=9E)
!
!
Thèmes'des'recherches''
HI)!9E)EJE8K:9E)8>L=;9M6;8=8>L=;9)N&"OP)5>C7QC>=)6C86;8)98)5>C7QC>=)R6=79)S)
"#$!$%$&'(#$!)*!$+,&!-#!.#&/&$!(+-01#$!23,3&/40#$5!#6&78(#(#,&!-/9#7$/:/3$!#&!;<+,-;,&$!-;,$!
1#$!23,+(#$!<;=&37/#$>!?#$!$%$&'(#$!$+,&!=+(.+$3$!-#!-#06!2',#$5!=+-;,&!7#$.#=&/9#(#,&!.+07!
0,#!.7+&3/,#!&+6/40#!#&!$+,!;,&/&+6/,#!$.3=/:/40#>!@1$!$+,&!1+=;1/$3$!$07!1#$!313(#,&$!23,3&/40#$!
(+</1#$!A.1;$(/-#$5! .B;2#$5! &7;,$.+$+,$C! #&! -;,$! 1#$! =B7+(+$+(#$5! #,! 23,37;1! -;,$! 1#$! D1+&$!
23,+(/40#$>!"#07!.#&/&#!&;/11#5!1#07!+72;,/$;&/+,!#,!+.37+,!#&!1#07!-3.#,-;,=#!(0&0#11#!.#7(#&!
0,!&7;,$:#7&!B+7/E+,&;1!;/$3!-#!=#$!$%$&'(#$5!(3=;,/$(#!.7+<;<1#!.;7!1#40#1!=#$!$%$&'(#$!+,&!
#,9;B/$!1#$!=B7+(+$+(#$!<;=&37/#,$>!"#07!:+,=&/+,!40;,-!/1$!$+,&!1+=;1/$3$!$07!1#$!.1;$(/-#$!#$&!
-#! =+,&7/<0#7! F! 1#07! (;/,&/#,&!-;,$! 1#$! .+.01;&/+,$! <;=&37/#,,#$! #,! =7+/$$;,=#>! G;7! =+,&7#5!
1;H1#$!:+,=&/+,A$C!-#!=#$!$%$&'(#$!40;,-!/1$!$+,&!1+=;1/$3$!-;,$!1#$!=B7+(+$+(#$!7#$&#!$0I#&&#$!F!!
-3<;&>!!
J+0$!;9+,$!73=#((#,&! .73-/&!-#!,+09#11#$!:;(/11#$!-#!&+6/,#$!#&!-K;,&/&+6/,#$!.;7!-/::37#,&#$!
;..7+=B#$!</+/,:+7(;&/40#$>!";!9;1/-;&/+,!#6.37/(#,&;1#!-#!=#$!$%$&'(#$!#$&!#,! =+07$!-;,$! E.#
coli5!-#!(8(#! 40#!1K;,;1%$#!-#$!;=&/9/&3$!&+6/40#$!#&! 1;!7#=B#7=B#!-#! 1#07$!=/<1#$>!LK;0&7#!.;7&5!
,+0$!,+0$!/,&37#$$+,$!;06!(3=;,/$(#$!(+13=01;/7#$!7#$.+,$;<1#$!-#!1K;=&/9;&/+,!-#$!$%$&'(#$!
)*!#&!-#$!=+,-/&/+,$!-;,$!1#$40#11#$!/1$!$K;=&/9#,&>!L;,$!1;!(8(#!1/2,#!-#!7#=B#7=B#5!,+0$!,+0$!
/,&37#$$+,$! ;0! .B3,+(',#! -#! .#7$/$&;,=#5! .B3,+(',#! .;7! 1#40#1! 0,#! :;/<1#! .7+.+7&/+,! -#!
<;=&37/#$! ;0! $#/,! -K0,#! .+.01;&/+,! #$&! =;.;<1#! -#! &+137#7! 1;! .73$#,=#! -K0,! &7;/&#(#,&!
;,&/</+&/40#>!?#!.B3,+(',#!#$&!1/3!;06!$%$&'(#$!)*!(;/$!,+0$!#6.1+7+,$!32;1#(#,&!-#$!!9+/#$!
/,-3.#,-;,&#$!-#!=#$!$%$&'(#$>!
"K+<I#=&/:!21+<;1!-#!=#!.7+I#&!#$&!-K;..73B#,-#7!1;!-/9#7$/&3!-#$!$%$&'(#$!)*5!-#!-3(/,#7!=#!
40/! ;! :;/&! 1#07! $0=='$! 39+10&/:! #&! -#! (/#06! =+(.7#,-7#! 1#07$A$C! 7M1#A$C! -;,$! 1;! .B%$/+1+2/#!
<;=&37/#,,#>!?#$!40#$&/+,$!$+,&!;<+7-3#$!.;7!0,#!;..7+=B#!(01&/-/$=/.1/,;/7#!=+(.7#,;,&!-#!1;!
</+/,:+7(;&/40#5!-#!1;!(/=7+</+1+2/#!(+13=01;/7#5!-#!1;!</+=B/(/#!#&!</+1+2/#!$&70=&07;1#!#&!-#!1;!
(/=7+$=+./#!F!:10+7#$=#,=#!;0!,/9#;0!-#!1;!=#1101#!0,/40#>!
!
TI)%4@C?68=>;)@?>U6?9)BV9W)E.#coli)
"#$! 73201;$! 21+<;06! $+,&! -#$! (+13=01#$! A*NJ! +0! .7+&3/,#$C! =+,&7M1;,&! 1K#6.7#$$/+,! -K0,!
27;,-! ,+(<7#! -#! 2',#$! $0/&#! F! 0,! =B;,2#(#,&! #,9/7+,,#(#,&;06>! L/::37#,&$! 73201;$!
21+<;06! ;2/$$#,&! F! -/::37#,&$! ,/9#;06! -#! 1K#6.7#$$/+,! -K0,! 2',#! A&7;,$=7/.&/+,5! &7;-0=&/+,! #&!
.+$&O&7;-0=&/+,,#1C>! "K#6.7#$$/+,! -#$! 73201;$! 21+<;06! #$&! #11#O(8(#! $+0(/$#! F! -#$!
73201;&/+,$>! J+0$! ,+0$! /,&37#$$+,$! .;7&/=01/'7#(#,&! ;0! 73201;! ?$7*! A=;7<+,! $&+7;2#!
7#201;&+7!*C!/(.1/403!-;,$!1;!73201;&/+,!-#!1;!:+7(;&/+,!-#$!</+:/1($!#&!-0!(3&;<+1/$(#!=#,&7;1!
-0! =;7<+,#>! J+0$! ;9+,$! (+,&73! 40#! =#! 2',#! #$&! #$$#,&/#1! F! 1;! =7+/$$;,=#! -KE.# coli>! L#$!
#6.37/#,=#$! -K39+10&/+,! P#,! &0<#K! +,&! .#7(/$! -K+<&#,/7! -#$! (0&;,&$! =+(.#,$;&+/7#$>! "#!
$340#,Q;2#! =+(.1#&! #&! 1K;,;1%$#! -0! 23,+(#! -#! =#$! $+0=B#$! P39+103#$K! $+,&! #,! =+07$>! L#! .10$5!
,+0$! 9+01+,$! /-#,&/:/#7! -#! ,+09#11#$! 9+/#$! 732013#$! .;7! =#$! 73201;$5! ;::/,#7! 1;!