Cancer et fonctions cognitives

55èmesèmes Journées Scientifiques Journées Scientifiques –– 10 et 11 mai 201210 et 11 mai 2012–– DeauvilleDeauville
Cancer et fonctions cognitives
Programme Phare Axe 4
Présenté par Pr F Joly, Caen

Is cancer and cognition a real problem nowadays?
For the patients : definitely yes
Hurricane Voice Breast Cancer Survey
(2007)
More than 2/3rds complain of cognitive
disorders
North West Canceropole survey
• 551 French and Belgium Patients
(2010)
•
41% complain of cognitive disorders
ICCTF International Cognition and Cancer Task Force Conference ICCTF International Cognition and Cancer Task Force Conference March 15March 15--17 17 thth 2012 2012 –– PARIS PARIS -- FRANCEFRANCE
Memory dysfonction
during and after CT 98%
Negative impact on day to
day lives 62%
•
41% complain of cognitive disorders
with chemo
• 72% consider it a major side effect
(Survey, Lefel at al, Submitted)
Fatigue (62%)
Anxiety, stress
26%
Treatment (45%)

Is cancer and cognition a real problem, nowadays?
For the research scientific community
60
80
100
120
140
160
180
num
publications
ICCTF International Cognition and Cancer Task Force Conference ICCTF International Cognition and Cancer Task Force Conference March 15March 15--17 17 thth 2012 2012 –– PARIS PARIS -- FRANCEFRANCE
0
20
40
2002-
2007 2008- 2009 2010- 2012
Pubmed : 302 Abstracts selected on words “cognition
and cancer” in title and abstract between 2002-2012
definitely yes

Is cancer and cognition a real problem, nowadays ?
For medical oncologists
Yes,but until now, not definitely yes
Why?
Some doubts on the reality of “chemobrain” and the
impact on the quality of life of their patients
ICCTF International Cognition and Cancer Task Force Conference ICCTF International Cognition and Cancer Task Force Conference March 15March 15--17 17 thth 2012 2012 –– PARIS PARIS -- FRANCEFRANCE
impact on the quality of life of their patients
They don’t have clear explanations on the mechanisms
and which drugs may be involved
Neuropsychological tests are difficult to organize in routine
They have no solution to prevent and/or treat cognitive
decline of their patients or to help them to cope with