Cognition and Cancer ICCTF Meetings  Workshops Congres/Symposium

1
Cognition and Cancer ICCTF Meetings
Workshops
2003 : Benff (Canada)
2005 : Venice (Italy)
2008 : Amsterdam (Netherlands)
Congres/Symposium
2010: New York (USA)
2012: Paris (France)
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
2012:
Paris
(France)

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Meeting organized by North West Canceropole,
INCa 7 Canceropoles
Creation of the INCa 2003
(French National Cancer Inst)
(French
National
Cancer
Inst)
First Cancer plan (2003-2009)
6 operational programs with 70 measures
2nd National cancer plan (2009-2013)
New programs and main areas
Research
and
innovation
Observation
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Research
and
innovation
,
Observation
,
Prevention and screening ,Care , Life
during and after cancer
Research axis of the North West Canceropole
5 axis of research
Development and validation prognostic
and
p
redictive biomarkers to thera
p
eutic innovation
pp
Tumor onset and progression in malignant blood
disorders
Multimodality targeting in Oncology
Cancer and neurosciences
Cancer, individuals and society
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Multi-disciplinary flagships (from labs to bench)
Development of integrated multidisciplinary research
program of emerging topics : Cognition and cancer

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Steering Committee
Tim Alhes (NY, US)
Sanne Schagen (Amsterdam, Netherlands)
Janette Vardy (Sydney, Australia)
Jeff Weffel (Houston, US)
ICCTF 2012 Organization
Organizing Committee
Tim Alhes (NY, US)
Sanne Schagen (Amsterdam, Netherlands)
Janette Vardy (Sydney, Australia)
Jeff Weffel (Houston, US)
Florence JOLY (Caen, France)
Paris local organization (Canceropole)
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Advisory Board
Patricia Ganz (Los Angeles, US)
Ian Tannock (Toronto, Canada)
Jimmie Holland (NY, US)
Christina Meyer (Houston, US)
Frits van Dam (Amsterdan, Netherlands)
Sophie Broutin (Lille France)
Veronique Pancre (Lille France)
Florence JOLY (Caen, France)
140 participants (ICCTF, Paris, 2012)
USA
France
Netherlands
Netherlands
Canada
Belgium
UK
Australia
Denmark
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Singapore
Spain
Germany
Norwa
y

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Organization of the 3 days
Late registrations
Breaks, lunches on site (Espace St Martin)
2
y
oun
g
investi
g
ators awards on Saturda
y
afternoon
yg g y
Boat cruise, Thursday evening 15th March
MELODY BLUES - Quai de Bercy Aval - 75012 PARIS
Departure by bus at 19h15 from Espace St Martin
Return by bus at 22h30 to Espace St Martin
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Is Cancer and cognition a real problem nowadays?
For the patients : definitely yes
551 French and Belgian Patients
Memory dysfonction
during and after CT 98%
Hurricane Voice Breast Cancer
Survey (2007)
More than 2/3rd complain of cognitive
disorders
•
551
French
and
Belgian
Patients
• 41% complain of cognitive disorders
with chemo
• 72% consider it is a major side effect
(Survey, Lefel at al, Submitted)
Fatigue (62%)
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Negative impact on day to
day lives 62%
Fatigue
(62%)
Anxiety, stress
26%
Treatment (45%)

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Is Cancer and cognition a real problem, nowadays?
For the research scientific community
180
0
20
40
60
80
100
120
140
160
2002-
2007 2008- 2009 2010- 2012
num
publications
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
Pubmed : 302 Abstracts selected on words “cognition
and cancer” in title and/or abstract between 2002-2012
Definitely yes
Is Cancer and cognition a real problem, nowadays ?
For the medical oncologists
Yes
but until now
not definitely
yes
Yes
,
but
until
now
,
not
definitely
yes
Why?
Some doubts on the reality of the “chemobrain”
They don’t have clear explanations on the mechanisms
and which drugs may be involved
Neuropsychological tests are difficult to organize in routine
ICCTF International Cognition and Cancer ICCTF International Cognition and Cancer TaskTask Force Force ConferenceConference March 15March 15--17 17 thth 2012 2012 ––PARIS PARIS --FRANCEFRANCE
They have no solution to prevent and/or treat cognitive
decline of their patients or to help them to cope with