Anne Brédart Docteur en Psychologie Médicale, HDR Thèmes de

Anne Brédart
Docteur en Psychologie Médicale, HDR
Psychologue, Unité de Psycho-oncologie, Institut Curie, Paris
Laboratoire de Psychopathologie et Processus de Santé (LPPS)
Équipe 3
Tél.: +33 (0)1 44 32 40 33
Thèmes de recherche
Mon activité de recherche relève du champ de la psycho-oncologie. Elle porte sur le retentissement psychologique et
interpersonnel du cancer et de ses traitements, sur les facteurs psychologiques entravant ou favorisant l’adaptation
psychologique à la maladie et à sa prise en charge, et sur le développement et l’évaluation d’interventions psychosociales en
oncologie. Les recherches mises en place suivent les avancements de la cancérologie et de ses modes de prise en charge.
Elles s’adressent ainsi aux enjeux psychologiques de l’identification d’une mutation génétique prédisposant au cancer ou
permettant de cibler les thérapeutiques, des essais cliniques de nouveaux protocoles de traitement. A ce titre, je m’intéresse à
l’expérience de la qualité de vie, du bien-être, de la satisfaction vis-à-vis des soins, à la spécification de ces vécus et leur
évaluation quantitative. Je coordonne et participe aux recherches menées par le groupe qualité de vie de l’Organisation
Européenne de Recherche et de Traitement du Cancer (EORTC), visant la mise au point et la validation internationale de ce
type d’outils. Mes recherches en psycho-oncologie ont été menées dans différents centres d’oncologie à Bruxelles, à Milan et,
depuis 2000, à l’Institut Curie à Paris, je coordonne une équipe de recherche dont les travaux portent sur les difficultés et
les besoins en soins de support et sur l’amélioration de la communication médecin/patient en oncologie.
Publications
Articles principaux
Brédart, A., Kop, J. L., De Pauw, A., Caron, O., Fajac, A., Noguès, C., Stoppa-Lyonnet, D., Dolbeault, S. (2016). Effect on
perceived control and psychological distress of genetic knowledge in women with breast cancer receiving a BRCA1/2 test
result. Breast. 2016 Nov 9;31:121-127. doi: 10.1016/j.breast.2016.10.024. [Epub ahead of print] PubMed PMID: 27837705.
Wheelwright, S. J., Hopkinson, J. B., Darlington, A. S., Fitzsimmons, D. F., Fayers, P., Balstad, T. R., , Hammerlid,Brédart, A.
E., Kaasa, S., Nicolatou-Galitis, O., Pinto, M., Schmidt, H., Solheim, T. S., Strasser, F., Tomaszewska, I. M., Johnson, C. D.;
EORTC Quality of Life Group. Development of the EORTC QLQ-CAX24, a questionnaire for cancer patients with cachexia. J
Pain Symptom Manage. pii: S0885-3924(16)30765-5. doi:10.1016/j.jpainsymman.2016.09.010.
Brédart, A., Beaudeau, A., Young, T., Moura De Alberquerque Melo, H., Arraras, J. I., Friend, L., Schmidt, H., Tomaszewski,
K. A., Bergenmar, M., Anota, A., Costantini, A., Marchal, F., Tomaszewska, I. M., Vassiliou, V., Chie, W. C., Hureaux, J.,
Conroy, T., Ramage, J., Bonnetain, F., Kulis, D., Aaronson, N. K.; EORTC Quality of Life Group. (2016). The European
organization for research and treatment of cancer - satisfaction with cancer care questionnaire: revision and extended
application development. Psychooncology. doi: 10.1002/pon.4127.
Brédart, A., Bodson, S., Le Tourneau, C., , Bonnetain, F., Beaudeau, A., Coquan, E., Dolbeault, S. et Paoletti, X.Flahault, C.
(2016). Patients' perceived tolerance of side effects in phase I cancer clinical trials: A qualitative study. Eur J Cancer Care. doi:
10.1111/ecc.12596.
Gaujal L., Renou M., Dujaric ME., Baffert S., Tardivon A., Kriegel I., Buecher B., Girod A., Grosset L., Asselain B., Rouzier R.,
et Alran S. (2016). First outpatient satisfaction questionnaire with day-surgery in a French comprehensive cancerBrédart A.
center]. , 103(4):330-5.Bull Cancer
Brédart , Merdy O, Sigal-Zafrani B, Fiszer C, Dolbeault S. et Hardouin JB. (2016). Identifying trajectory clusters in breastA
cancer survivors' supportive care needs, psychosocial difficulties, and resources from the completion of primary treatment to 8
months later. , 24(1):357-66. Support Care Cancer
Brédart, A., ., Copel, L., Leufroy, M., Mino, J.-C., Boiron, C., Dolbeault, S. et Kop, J.-L. (2016). Breast cancerUntas, A
survivors’ supportive care needs, post-traumatic growth and satisfaction with doctors’ interpersonal skills in relation to physical
activity eight months after the end of treatment: a prospective exploratory study. , 90(3), 151-159.Oncology
DOI:10.1159/000443766 (IF: 2.152)
Dolbeault, S. et (2016). La sexualité intégrée dans la dynamique des soins de support en oncologie. Brédart, A. Rev Infirm,
65(222):24-6.
Brédart, A., Coens, C., Aaronson, N., Chie, W. C., Efficace, F., Conroy, T., et al. (2007). Determinants of patient satisfaction in
oncology settings from European and Asian countries: preliminary results based on the EORTC IN-PATSAT32 questionnaire.
(2), 323-330.Eur J Cancer, 43
This, P., de la Rochefordiere, A., Brédart, A., Asselain, B., Poinsot, R., Dolbeault, S., et al. (2006). Quality of life in a
randomized control trial? Comments concerning MA 17. (24), 4038; author reply 4038-4039.J Clin Oncol, 24
Brédart, A., Bottomley, A., Blazeby, J. M., Conroy, T., Coens, C., D'Haese, S., et al. (2005). An international prospective study
of the EORTC cancer in-patient satisfaction with care measure (EORTC IN-PATSAT32). (14), 2120-2131.Eur J Cancer, 41
Brédart, A., & Petit, J. Y. (2005). Partial mastectomy: a balance between oncology and aesthetics? (3), 130.Lancet Oncol, 6
Delvaux, N., Razavi, D., Marchal, S., Brédart, A., Farvacques, C., & Slachmuylder, J. L. (2004). Effects of a 105 hours
psychological training program on attitudes, communication skills and occupational stress in oncology: a randomised study. Br
(1), 106-114.J Cancer, 90
Brédart, A., Cayrou, S., Dolbeault, S. Letter to the Editor: Re: Systematic review of psychological therapies for cancer patients:
overview and recommendantions for future research. J Nat Cancer Inst 2002, 4 (94): 1810.
Colleoni, M., Mandala, M., Peruzzotti, G., Robertson, C., Brédart, A., Goldhirsch, A. (2000). Depression and degree of
acceptance of adjuvant cytotoxic drugs. (9238), 1326-1327.Lancet, 356
Bjordal, K., de Graeff, A., Fayers, P. M., Hammerlid, E., van Pottelsberghe, C., Curran, D., et al. (2000). A 12 country field
study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head
and neck patients. EORTC Quality of Life Group. (14), 1796-1807.Eur J Cancer, 36
Brédart, A., Razavi, D., Robertson, C., Didier, F., Scaffidi, E., & de Haes, J. C. (1999). A comprehensive assessment of
satisfaction with care: preliminary psychometric analysis in an oncology institute in Italy. (7), 839-846.Ann Oncol, 10
Razavi, D., Delvaux, N., Marchal, S., Brédart, A., Farvacques, C., & Paesmans, M. (1993). The effects of a 24-h psychological
training program on attitudes, communication skills and occupational stress in oncology: a randomised study. Eur J Cancer,
(13), 1858-1863.29A
Razavi, D., Delvaux, N., Brédart, A., Paesmans, M., Debusscher, L., Bron, D., et al. (1992). Screening for psychiatric disorders
in a lymphoma out-patient population. (11), 1869-1872.Eur J Cancer, 28A
En premier auteur
Brédart, A., Kop, J-L., Fall, M., Pelissier, S., Simondi, C., Dolbeault, S., Livartowski A, Tardivon A (2011). Anxiety and specific
distress in women at intermediate and high risk of breast cancer before and after surveillance by magnetic resonance imaging
and mammography versus standard mammography. Psychooncology. Aug 3
Brédart, A., Kop, J-L., Fall, M., Pelissier S, Simondi C, Dolbeault S, Livartowski A, Tardivon A; for the Magnetic Resonance
Imaging study group (STIC IRM 2005) (2011). Perception of care and experience of examination in women at risk of breast
cancer undergoing intensive surveillance by standard imaging with or without MRI. , 405-413.Patient Educ Couns
Brédart, A., Morvan, E., Savignoni, A., Giraud, P. Respiratory Gated Radiotherapy Study Group Stic-Rar 2003 (2011).
Patient's perception of care quality during radiotherapy sessions using respiratory gating techniques: validation of a specific
questionnaire. , 29(2), 145-52.Cancer Invest
Brédart, A., Dolbeault, S., Savignoni, A., Besancenet, C., This, P., Giami, A., Michaels. S., Flahault, C., Falcou, MC., Asselain,
B., Copel, L. (2011). Prevalence and associated factors of sexual problems after early-stage breast cancer treatment: results
of a French exploratory survey. , 20(8), 841-50.Psychooncology
Brédart, A., Sultan, S., Regnault, A. (2010). Patient satisfaction instruments for cancer clinical research or practice. Expert Rev
, 10(2), 129-41.Pharmacoecon Outcomes Res
Brédart, A., Dolbeault, S., Savignoni, A., Simard, S., Gomme, S., Asselain, B., Copel, L. (2009). Pilot evaluation of a French
interdisciplinary supportive care department. , 17(12), 1507-16.Support Care Cancer
Brédart, A., Buron, C., Doz, M., & Tardivon, A. (2008). [French adaptation of a mammography questionnaire (MGQ)]. Bull
(2), 253-258.Cancer, 95
Brédart, A., Swaine-Verdier, A., Dolbeault, S. (2007). Traduction/adaptation française de l'échelle "Body Image Scale" (BIS)
évaluant la perception de l'image du corps chez des femmes atteintes de cancer du sein. (1 , 24-30.Psycho-Oncologie, 1 )
Brédart, A. (2006). Evaluation de la fatigue chez les patients atteints de cancer: développement d’un questionnaire par le
groupe qualité de vie de l’EORTC. (3), 15-18.Réflexions en Médecine Oncologique, 11
Brédart, A. (2006). Evaluation de la qualité de vie en oncologie : Méthodes et applications. (5), 448-452.Oncologie, 8
Brédart, A., Mignot, V., Rousseau, A., Dolbeault, S., Beauloye, N., Adam, V., et al. (2005). [Cancer patient's satisfaction
assessment using the EORTC QLQ-SAT32: comparison between self-assessment and interview response]. Rev Epidemiol
, 1S31-38.Sante Publique, 53 Spec No 1
Brédart, A., Dolbeault, S. (2005). Evaluation de la qualité de vie en oncology : I Définition et objectifs. Revue Francophone de
, 7-11.Psycho-Oncologie, 1
Brédart, A., Dolbeault, S. (2005). Evaluation de la qualité de vie en oncology : II Méthodes. Revue Francophone de
13-17.Psycho-Oncologie, 1,
Brédart, A., Bouleuc, C., Dolbeault, S. (2005). Doctor-Patient communication and patient satisfaction in oncology. Current
, 351-354.Opinion in Oncology, 17
Brédart, A., Mignot, V., Rousseau, A., Dolbeault, S., Beauloye, N., Adam, V., et al. (2004). Validation of the EORTC
QLQ-SAT32 cancer inpatient satisfaction questionnaire by self- versus interview-assessment comparison. Patient Educ
(2), 207-212.Couns, 54
Brédart, A., Robertson, C., Razavi, D., Batel-Copel, L., Larsson, G., Lichosik, D., et al. (2003). Patients' satisfaction ratings
and their desire for care improvement across oncology settings from France, Italy, Poland and Sweden. Psychooncology, 12
(1), 68-77.
Brédart, A., Razavi, D., Robertson, C., Brignone, S., Fonzo, D., Petit, J. Y., et al. (2002). Timing of patient satisfaction
assessment: effect on questionnaire acceptability, completeness of data, reliability and variability of scores. Patient Educ
(2), 131-136.Couns, 46
Brédart, A., Bottomley, A. (2002). Treatment satisfaction as an outcome measure in cancer clinical treatment trials. Expert
), 89-98.Rev. Pharmacoeconomics and Outcome Res, 2(6
Brédart, A., Razavi, D., Robertson, C., Batel-Copel, L., Larsson, G., Lichosik, D., et al. (2001). A comprehensive assessment
of satisfaction with care: preliminary psychometric analysis in French, Polish, Swedish and Italian oncology patients. Patient
(3), 243-252.Educ Couns, 43
Brédart, A., Autier, P., Riccardo, A., Audisio, A., & Geraghty, J. G. (2001). Psychosocial dimensions of BRCA testing: an
overshadowed issue. (2), 96-99.Eur J Cancer Care (Engl), 10
Brédart, A., Razavi, D., Robertson, C., Didier, F., Scaffidi, E., Fonzo, D., et al. (2001). Assessment of quality of care in an
oncology institute using information on patients' satisfaction. (2), 120-128.Oncology, 61
Brédart, A., Didier, F., Robertson, C., Scaffidi, E., Fonzo, D., Costa, A., et al. (1999). Psychological distress in cancer patients
attending the European Institute of Oncology in Milan. (4), 297-302.Oncology, 57
Brédart, A., Autier, P., Audisio, R. A., & Geragthy, J. (1998). Psycho-social aspects of breast cancer susceptibility testing: a
literature review. (3), 174-180.Eur J Cancer Care (Engl), 7
Brédart, A., Razavi, D., Delvaux, N., Goodman, V., Farvacques, C., & Van Heer, C. (1998). A comprehensive assessment of
satisfaction with care for cancer patients. (6), 518-523.Support Care Cancer, 6
Brédart, A., Razavi, D. (1997). The preservation of well-being in cancer patients: role of quality of life and satisfaction with care
assessments. /97, 16-17.Oncology in Practice, 1
Brédart, A., Delvaux, N. (1995). Psychological and social morbidity in oncology: key challenges for implementation of
supportive interventions. (14), 1-2.Topics on Supportive Care in Oncology, 1/95
En auteur directeur
Dolbeault, S., Boistard, B., Meuric, J., Copel, L., Brédart, A (2011). Screening for distress and supportive care needs during
the initial phase of the care process: a qualitative description of a clinical pilot experiment in a French cancer center.
, 20(6), 585-93.Psychooncology
Dolbeault S, Brédart A. [Announcing cancer diagnosis: which communication difficulties from professional and from patient's
side? Which possible improvements?]. Bull Cancer. 2010;97(10):1183-94.
Jayasekara, H., Rajapaksa, L., Brédart, A. (2008). Psychometric properties of the cancer in-patient satisfaction with care
measure of the European Organization for Research and Treatment of Cancer (EORTC IN-PATSAT32) in South Asian cancer.
, 1-6.Intern J Qual in Health Care
Poinsot, R., Altmeyer, A., Conroy, T., Savignoni, A., Asselain, B., Leonard, I., et al. (2006). [Multisite validation study of
questionnaire assessing out-patient satisfaction with care questionnaire in ambulatory chemotherapy or radiotherapy
treatment]. (3), 315-327.Bull Cancer, 93
Dolbeault, S., Flahault, C., Stoppa-Lyonnet, D., & Brédart, A. (2006). Communication in genetic counselling for breast/ovarian
cancer. , 23-36.Recent Results Cancer Res, 168
Autres
Lelorain, S., Brédart, A., Dolbeault, S., Sultan, S. (2012). A systematic review of the associations between empathy measures
and patient outcomes in cancer care. , Jan 11.Psychooncology
Nguyen, TV., Bosset, JF., Monnier, A., Fournier, J., Perrin, V., Baumann, C., Bredart, A., Mercier, M. (2011). Determinants of
patient satisfaction in ambulatory oncology : a cross sectional study based on the OUT-PATSAT35 questionnaire. BMC
, 11(1), 526.Cancer
Suchocka-Capuano, A., Brédart, A., Dolbeault, S., Rouic ,LL., Lévy-Gabriel, C., Desjardins, L., Flahault, C., Bungener, C
(2011). [Quality of life and psychological state in patients with choroidal melanoma: longitudinal study]. ,Bull Cancer
98(2):97-107.
Leblond, D., Brédart, A., Dolbeault, S., De Pauw, A., Stoppa Lyonnet, D., Flahault, C., Sultan, S (2011). [Cognitive, emotional
and behavioral impact of an uncertain outcome after study of BRCA1/2: review of the literature]. , 8(2):184-98.Bull Cancer
Grenier, C., De Jésus, A, Farsi, F, Marx G, Brédart, A., Peixoto O, Gameroff S, Tursz T (2010). [Communication around the
cancer diagnosis: patient satisfaction and process quality in French Comprehensive Cancer Centers]. , 97(10),Bull Cancer
1163-72.
Bouleuc, C, Bredart, A, Dolbeault, S, Ganem G, Copel L (2010). [How to improve cancer patients' satisfaction with medical
information]. , 97(10), 1173-81.Bull Cancer
Johnson C, Fitzsimmons D, Gilbert J, Arrarras JI, Hammerlid E, Bredart A, Ozmen M, Dilektasli E, Coolbrandt A, Kenis C,
Young T, Chow E, Venkitaraman R, Howse F, George S, O'Connor S, Yadegarfar G; EORTC Quality of Life Group (2010).
Development of the European Organisation for Research and Treatment of Cancer quality of life questionnaire module for
older people with cancer: The EORTC QLQ-ELD15. , 46(12), 2242-52.Eur J Cancer
Ollivier L, Apiou F, Leclère J, Sévellec M, Asselain B, Brédart A, Neuenschwander S (2009). Patient experiences and
preferences: development of practice guidelines in a cancer imaging department. Cancer Imaging, 9 Spec NoA:S92-7.
Scott NW, Fayers PM, Aaronson NK, Bottomley A, de Graeff A, Groenvold M, Gundy C, Koller M, Petersen MA, Sprangers
MA; EORTC Quality of Life Group and the Quality of Life Cross-Cultural Meta-Analysis Group (2009). Differential item
functioning (DIF) in the EORTC QLQ-C30: a comparison of baseline, on-treatment and off-treatment data. ,Qual Life Res
18(3), 381-8.
Dolbeault S, Cayrou S, Brédart A, Viala AL, Desclaux B, Saltel P, Gauvain-Piquard A, Hardy P, Dickes P (2009). The
effectiveness of a psycho-educational group after early-stage breast cancer treatment: results of a randomized French study.
, 18(6), 647-56.Psychooncology
Fitzsimmons D, Gilbert J, Howse F, Young T, Arrarras JI, Brédart A, Hawker S, George S, Aapro M, Johnson CD (2009). A
systematic review of the use and validation of health-related quality of life instruments in older cancer patients. ,Eur J Cancer
45(1), 19-32.
Dolbeault, S., Brédart, A., Mignot, V., Gauvain-Piquard, A., Mandereau, L., Asselain, B., Medioni, J. (2008). Screening for
psychological distress in two French cancer centres: feasibility and performance of the adapted distress thermometer.
, 6(2):107-17.Palliative and Supportive Care Journal
Adam, V., Brédart, A., Didier, F., Dolbeault, S., Oppenheim, D., Reich, M., Scaffidi, E., Seigneur, E. (2007). 8th World
Congress of Psycho-Oncology, 16-21 octobre 2006. Multidisciplinary psychosocial oncology: dialogue and interaction. Compte
rendu. , 146-151.Psycho-Oncologie
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Anne Brédart Docteur en Psychologie Médicale, HDR Thèmes de

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