PUBLICATIONS SCIENTIFIQUES

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PUBLICATIONS SCIENTIFIQUE
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1. H. AMRI, M. M. EL GAIED, M'HIRSI, Action de Me3N,2HF sur des Epoxydes Simples et
-Fonctionnels Dérivés d'un Monoterpène Bicyclo[3.1.1]Heptanique, J. Soc. Chim. Tunisie 1983, 10, 25.
2. H. AMRI, M. RAMBAUD, J. VILLIERAS, Esters -Méthyléniques par Addition d'Organolithiens ou
Magnésiens sur l'-(Hydroxyméthyl) Acrylate d'Ethyle et ses Dérivés en Présence de Cuivre (I),
J. Organomet . Chem. 1986, 308, C27.
3. H. AMRI, J. VILLIERAS, Hydroxyalkylation de la Méthylvinylcétone et de l'Acrylonitrile en présence
de 1,4-Diazabicyclo[2.2.2] Octane, Tetrahedron Lett. 1986, 27, 4307.
4. H. AMRI, J. VILLIERAS, Alkylation d'Acétates de Cyclénols Fonctionnels (5 et 6) Chaînons par les
Réactifs de Grignard et les Enolates Lithiens Catalysée (ou non) par les Sels de Cuivre (I). Synthèse
rapide de la (±)-Mitsugashiwalactone, Tetrahedron Lett. 1987, 28, 5521.
5. H. AMRI, M. M. EL GAIED, Action du Fluorhydrate de Timéthymamine Me3N,2HF sur quelques
-Epoxycétones dérivés du Cyclohexane, J. Soc. Chim. Tunisie 1989, 10, 13.
6. H. AMRI, J. VILLIERAS, A Short Large Scale Synthesis of (±) Sarkomycin Esters, Tetrahedron Lett.
1989, 30, 7381.
7. H. AMRI, M. M. EL GAIED, Ouverture Régiosélective des Epoxy-cis et trans-Isophorols et les
Composés Acylés Correspondants par le Difluorhydrate de Triméthymamine: Me3N,2HF, J. Fluorine
Chem. 1990, 46, 75.
8. H. AMRI, M. RAMBAUD, J. VILLIERAS, Esters -Méthyléniques par Substitution d'Ethers et
d'Acétates Dérivés de l'-(Hydroxyméthyl) Acrylate d'Ethyle, J. Organomet. Chem. 1990, 384, 1.
9. H. AMRI, M. RAMBAUD, J. VILLIERAS, Substitution Nucléophile d'Acétates de Cyclénols
Allyliques Fonctionnels par des Organométalliques en Présence de Sels Cuivreux. Application à une
Synthèse Rapide de la (±)-Mitsugashiwalactone, Tetrahedron 1990, 46, 3535.
10. H. AMRI, M. M. EL GAIED, J. VILLIERAS, Hydroxyalkylation of Diethylvinyl-Phosphonate in the
Presence of DABCO, Synthetic Commun. 1990, 20, 659.
11. T. BEN AYED, H. AMRI et M. M. EL GAIED Addition of Bromine to '-(Functional Alkyl)
-Insaturated Esters. Stereoselective Synthesis of -Haloderivatives, Tetrahedron 1991, 47, 9621.
12. T. BEN AYED, H. AMRI, M. M. EL GAIED, J. VILLIERAS, Direct Substitution of Vinylic Bromine
by an Amino Group : Synthesis of Dimethyl -(Aminomethylene) Glutaric Acid Esters, J. Soc. Chim.
Tunisie 1992, vol III, 219.
13. H. AMRI , M. M. EL GAIED, T. BEN AYED, J. VILLIERAS, Nouvelle Synthèse
d'-(1-Hydroxy-Alkyl)--Lactames, Tetrahedron Lett. 1992, 33, 6159.
14. H. AMRI , M. M. EL GAIED, T. BEN AYED, J. VILLIERAS, Synthèse de -Lactames et de
Perhydro-1,2-Pyridazin-3-Ones Polyfonctionnels, Tetrahedron Lett. 1992, 33, 7345.

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15. F. AMMADI , M. M. CHAABOUNI, H. AMRI, A. BAKLOUTI, Synthesis of -Cyano--Fluoro--
Hydroxyesters, Synthetic Commun. 1993, 23, 2389.
16. I. BELTAIEF and H. AMRI , Substitution of Allylic Functional Acetates: Stereoselective Synthesis
of 2-Alkylidene-1,5-Ketoesters, Synthetic Commun. 1994, 24, 2003.
17. T. BEN AYED, M. M. EL GAIED and H. AMRI , Stereoselective Synthesis of Some Dialkyl
(E)-2-Bromomethylene Glutarates, Synthetic Commun. 1995, 25, 2981.
18. T. BEN AYED, H. AMRI , M. M. EL GAIED, J. VILLIERAS, Addition Conjuguée d'Amines
Primaires aux Composés Acryliques -(1-Hydroxy)Alkylés: Nouvelles Synthèse de - et de -Lactames
Polyfonctionnels, Tetrahedron 1995, 51, 9633.
19. T. BEN AYED and H. AMRI, A Convenient Synthesis of -Functional Alkyl Vinyl Ketones,
Synthetic Commun. 1995, 25, 3813.
20. V. DAMBRIN, M. VILLIERAS, C. MOREAU, H. AMRI, L. TOUPET, J. VILLIERAS, Copper(I)
Mediated Highly Diastereoselective Conjugate Addition of Grignard Reagents to
2-Silyloxycyclopentenecarboxylates, Tetrahedron Lett. 1996, 37, 6323.
21. S. BEN GHARBIA, R. BESBES, J. VILLIERAS, H. AMRI , Selected Reaction of (Z)-Dimethyl
-(Bromomethyl) Fumarate with Secondary Amines, Synthetic Commun. 1996, 26, 1685.
22. I. BELTAÏEF, R. BESBES, H. AMRI and J. VILLIERAS, TEAF Mediated Hydroxylation of Allylic
Bromide: A Facile Synthesis of 4-Methoxycarbonyl-2(5H)-Furanone, Tetrahedron Lett. 1997, 38, 813.
23. R. BESBES, M. VILLIERAS, H. AMRI , Improved Synthesis and Reaction of Dimethyl
-(Bromomethyl) Fumarate with Primary Amines, Indian . Org. Chem. 1997, 36B, 5.
24. A. CHAMAKH, M. M'HIRSI, H. AMRI, Stereospecific Synthesis of Methyl Vinyl Ketones,
Synthetic Commun. 1997, 27, 1157.
25. T. BEN AYED, M. M. EL GAIED, H. AMRI, Conjugate Addition of Grignards Reagents to
-Functional Enone Promoted by LiCuBr2, J. Soc. Chim. Tunisie 1997, Vol. IV, 13.
26. S. HBAIEB, T. BEN AYED and H. AMRI, New Efficient Synthesis of 3-Substituted 2-Cyano Allylic
Alcohols, Synthetic Commun. 1997, 27, 2825.
27. F. BEN AMOR, I. BELTAÏEF, R. BESBES, H. AMRI, Methyl 1-Benzyl-3-Cyclohexyl-2-
Oxopyrrolidine-2-Caboxylate, Acta Cryst. (C) 1997, C53 , 1919.
28. A. CHAMAKH, H. AMRI, A One Pot Synthesis of 4-Alkylidene Cyclohexen-2-ones, Tetrahedron
Lett. 1998, 39 , 375.
29. I. BELTAÏEF, S. HBAÏEB, R. BESBES, H. AMRI, M. VILLIERAS, J. VILLIERAS, A New and
Efficient Method for the Isomerization of Secondary Functional Allylic Alcohols into their Primary
Isomers, Synthesis 1998 , 1765.
30. I. BELTAÏEF, R. BESBES, H. AMRI, F. BEN AMOR, M. VILLIERAS, J. VILLIERAS, (Z)-
Dimethyl -(bromomethyl) Fumarate, an Efficient Intermediate for The Selective Synthesis of Dimethyl
3-Alkyl Itaconates and 2-Alkyl 3-Carbomethoxy--Lactames, Tetrahedron 1999, 55, 3949.
31. S. HBAÏEB, Z. LATIRI, H. AMRI, Stereoselective Synthesis of 2-Ethylidene-3-Amininitriles,
Synthetic Commun. 1999, 29, 981.

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32. V. DAMBRIN, M. VILLIERAS, J. LEBRETON, L. TOUPET, H. AMRI, J. VILLIERAS, Copper(I)
Mediated Highly Diastereoselective Conjugate Addition of Grignard Reagents to Functionalised
6-Membered Ring Cycloalkenols. Synthesis of Cyclohexanes Derivatives Substituted on Three
Contiguous Atoms, Tetrahedron Lett. 1999, 40, 871.
33. V. DAMBRIN, M. VILLIERAS, H. AMRI, J. LEBRETON, J. VILLIERAS, Copper(I) Mediated
Conjugate Addition of Grignard Reagents to 2-Oxoethylcyclohexanols. A Versatile, Efficient and
Diastereoselective Route to anti, Z 6-Alkyl-2-Trialkylsilyloxy-1-(2-Trimethylsilyloxypropylid-1-ene)-
Cyclohexanes, Synlett 1999, 1057.
34. S. HBAÏEB, H. AMRI, Stereoselective synthesis of 2-alkylidene-4-ketonitriles and -4-ketoesters,
J. Soc. Chim. Tunisie 1999, Vol IV, 671.
35. A. CHAMAKH, M. M'HIRSI, J. LEBRETON, J. VILLIERAS, H. AMRI, A Simplified Route to the
(E)-2-Alkylidene-1,4-Diketones, Synthesis 2000, 295.
36. T. BEN AYED, J. VILLIERAS, H. AMRI, A Stereoselective Synthesis of -(1-Hydroxyalkyl)--
Substituted Acrylic Acid Esters, Tetrahedron 2000, 56, 805.
37. F. BEJI, R. BESBES, H. AMRI, Synthesis of -Alkylidene--Ethoxycarbonyl Cyclopentanones and -
-Butyrolactones, Synthetic Commun. 2000, 30, 3947.
38. I. OUESLATI, R. ABIDI, H. AMRI, P. THUERY, M. NIERLICH, Z. ASFARI, J. HARROWFIELD,
J. VICENS, Cation-and Solvent-Induced Conformational Changes of 25,27-Dimethoxy-26, 28-Dimethyl
Ester-p-tert-Butylcalix[4]Arene, Tetrahedron Lett. 2000, 41, 8438.
39. A. SAMARAT, V. FARGEAS, J. VILLIERAS, J. LEBRETON, H. AMRI, A New Synthesis of
(±)-Homosarkomycin Ethyl Ester, Tetrahedron Lett. 2001, 42, 1273.
40. A. SAMARAT, J. LEBRETON, H. AMRI, Highly Stereoselective Synthesis of Dialkyl
2-Alkylidene Glutarates, Synthetic Commun. 2001, 31, 1675.
41. V. DAMBRIN, M. VILLIERAS, P. JANVIER, L. TOUPET, H. AMRI, J. LEBRETON, J.
VILLIERAS, Copper(I) Mediated Highly Diastereoselective Conjugate Addition of Grignard Reagents to
Functionalised Cycloalkenols : A General and Efficient Route for the Stereoselective Synthesis of
5- and 6-Membered Ring Trisubstituted Cycloalkanols, Tetrahedron 2001, 57, 2155.
42. M. SAÏDI, K. KHOTHARI, M. R. A. PILLAI, H. AMRI, H. D. SARMA, P. R. CHOUDHARI, T. P.
UNNIKRISHNAN, A. KORDE, Z. AZZOUZ, Cyclopentadienyl Technecium (99mTc) Tricarbonyl
Piperidine Conjugates : Bidistribution and Imaging Studies, Journal of Labelled Compounds and
Radiopharmaceuticals 2001, 44, 603.
43. R. ABIDI, I. OUESLATI, H. AMRI, P. THUERY, M. NIERLICH, Z. ASFARI, J. VICENS,
Synthesis, Structure and Complexing Properties of New Calix[4](Aza)Crowns, Tetrahedron Lett. 2001,
42, 1685.
44. L. KHALFALLAH BOUDALI, A. GHORBEL, H. AMRI, F. FIGUERAS, Propriétés Catalytiques de
la Montmorillonite Intercalée au Titane dans l'Oxydation de l'Alcool Allylique (E)-Hex-2-én-1-ol, C. R.
Acad. Sci. , Paris, Série IIc (Chimie) 2001, 4, 67.
45. F. BEJI, J. LEBRETON, J. VILLIERAS, H. AMRI, A Total Stereospecific Route to -Alkylidene--
Lactames, Tetrahedron 2001, 57, 9959.

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46. F. BEJI, J. LEBRETON, J. VILLIERAS, H. AMRI, Stereoselective and Stereospecific Synthesis of 2-
Alkylidene-3-Methylene Succinic Acid Dimethyl Esters, Synthetic Commun. 2002, 32, 3947.
47. H. KRAIEM, M. I. ABDALLAH, H. AMRI, First Synthesis of
2-Alkylation(Diethoxyphosphoryl)Methyl Acrylic Ethyl Esters, Tetrahedron Lett. 2003, 44, 553.
48. F. REZGUI, H. AMRI, M. M. EL GAIED Synthetic Methods for -Substituted Cyclic ,-Enones,
Tetrahedron 2003, 59, 1369.
49. A. BOUKADI, H. AMRI, Les Additifs Chimiques en Production Pétrolière : Définitions, principes,
rôles et mode de sélection, J. Soc. Chim. Tunisie 2003, 5, 275.
50. H. KRAIEM, T. TURKI, H. AMRI, Synthesis of 5- and 6-Acyl-1-Cyano- and -1-Ethoxycarbonyl
Cycloalkenes, Synthetic Commun. 2003, 33, 3261.
51. A. SAMARAT, Y. LANDAIS, H. AMRI, First Synthesis of (±)-bis-Homosarkomycin Ethyl Ester,
Tetrahedron Lett. 2004, 45, 2049.
52. A. SAMARAT, Y. LANDAIS, H. AMRI, Diastereoselective Synthesis of Functionalized
-Lactones, Synth. Commun. 2004, 34, 3707.
53. A. SAMARAT, Y. LANDAIS, H. AMRI, Enantioselective Synthesis of Functionalized
-Butyrolactones, Tetrahedron 2004, 60, 8949.
54. R. OULED SAAD, T. BEN AYED, J. LEBRETON, H. AMRI, Synthesis of Functinnalized
Homoallylsilanes, Synth. Commun. 2004, 34, 3719.
55. T. TURKI, J. VILLIERAS, H. AMRI, An Efficient Synthesis of Alkyl
-(Hydroxymethyl)Acrylates Induced by DABCO in an Aqueous Medium, Tetrahedron Lett. 2005, 46,
3071.
56. A. BOUKADI, H. AMRI, Flow Improvement of a Waxy Crude Oil by Chemical Additive Utilization,
Pakistan Journal of Biological Science 2005, 8, 1131.
57. R. OULED SAAD, T. TURKI, H. AMRI, A Short Synthesis of Functionalized Cyclic Homoallylsilanes, Synth. Commun.
2005, 35, 2921.
58. N. LAHMAR, T. BEN AYED, M. BELLASSOUED, H. AMRI, A Convenient Synthesis of
-Functionalized Cyclopentenones, Beilstein J. Org. Chem. 2005, I : 11.
59. R. OULED SAAD, H. AMRI, Action du Diazabicyclo [2.2.2] Octane et de KCN sur les Nitriles
,-Insatures -Bromomethyles : Synthese d’une Famille de (E, Z) Alkylmethylbutenedinitriles, J. Soc.
Chim. Tunisie 2005, 7, 239.
60. F. BEJI, F. BEN AMOR, H. AMRI, A. DRISS, Préparation et Structure Moléculaire du 1-Furan-2-
ylméthyl-4-(2-Hydroxyéthyl)-5-Oxopyrrolidine-3-(Furan-2-ylméthyl)Amide : C17H20N2O5, J. Soc . Chim.
Tu , 2005, 7, 277.
61. H. KRAIEM, T. TURKI, H. AMRI, Réaction d’Allylation Induite par l’Indium: Synthèse
d’-Diéthoxyphosphonométhylène--Butyrolactones J. Soc . Chim. Tu , 2005, 7, 67.
62. N. LAHMAR, J. AATAR, T. BEN AYED, H. AMRI, M. BELLASSOUED, A General Route to
-Alkyl (E)-,-Unsaturated Aldehydes, J. Organomet. Chem., 2006, 691, 3018.

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63. J. BEN KRAIEM, T. BEN AYED, H. AMRI, A Direct Synthesis of a-(Hydroxymethyl) and
-Alkyl-Vinyl-Alkyl Ketones, Tetrahedron Lett. 2006, 47, 7077.
64. M. S. M. PEARSON, R. OULED SAAD, T. DINTINGER, H. AMRI, M. MATHE- ALLAINMATA,
AND J. LEBRETON, Flexible Synthesis and Biological Evaluation of Novel 5-Deoxyadenophorine
Analogues, Bioorganic & Medicinal Chemistry Letters 2006, 16, 3262.
65. H. KRAIEM, H. AMRI, A New Alternative for the Synthesis of Highly Functionalized Phosphoryl
Derivatives, Phosphorus, Sulfur and Silicon 2007, 182, 2555.
66. T. TURKI, S. KHAMRI, H. AMRI, A Total Synthesis of (E)-11-Hydroxyundec-2-Enoic Acid,
A New Homologous Royal Jelly Acid, J. Soc . Chim. Tunisie 2007, 9, 17.
67. A. ARFAOUI, T. BEN AYED, H. AMRI, A New Synthesis of 3-(Bromomethyl) Furan-2,5-Dione, J.
Soc . Chim. Tunisie 2008, 10, 1.
68. S. KHAMRI, T. TURKI, H. AMRI, Stereoselective Synthesis of Functionalized 1,4-Dienes, Synth.
Commun. 2008, 38, 3277.
69. A. ARFAOUI, F. BÉJI, T. BEN AYED, H. AMRI, New selective synthesis of dimethyl
3-alkylamino itaconates, Synth. Commun. 2008, 38, 3717.
70. A. SAMARAT, J. BEN KRAÏEM, T. BEN AYED, H. AMRI, An Efficient Synthetic Route to
Functionalized -Lactams Tetrahedron 2008, 64, 9540.
71. S. KHAMRI, T. TURKI, H. AMRI, Highly Stereoselective Synthesis of Some -Branched
-(Phenylsulfonylmethyl) Acrylic Compounds, J. Soc . Chim. Tunisie 2008, 10, 149.
72. A. ARFAOUI, H. AMRI, An effective new access to ethyl 2-[(alkylamino)(cyano)methyl]
acrylates. First synthesis of ethyl 3-cyano-2-(hydroxymethyl) acrylate, Tetrahedron 2009, 65, 4904.
73. S. KHAMRI, H. AMRI, DABCO-mediated substitution of vinylic iodides:
synthesis of β-cyano Baylis-Hillman acetates, Tetrahedron 2009, 65, 4890.
74. A. ARFAOUI, F. BÉJI, H. AMRI, An effective synthesis of polysubstituted pyrroles from
(E)-dimethyl 2-(bromomethyl)-3-(diethoxyphosphoryl) fumarate, Synth. Commun. 2009, (Sous presse).
75. B. TOUMI, A. SAMARAT, A. HARIZI, H. AMRI, An Efficient Approach to the Synthesis of Ethyl
-Cyanoalkyl Acrylates by the HWE Olefination of Ethyl 2-(Diethoxyphosphoryl) Cyanoalkanoates,
Phosphorus, Sulfur and Silicon 2009, (Sous presse).
A - Communications orales
1. H. AMRI, M.RAMBAUD et J. VILLIERAS, Esters a-hydroxyméthylés par addition
d’organolithiens ou de magnésiens sur l’-(hydroxyméthyl.acrylate d’éthyle et ses dérivés en présence de
cuivre (I.. Congrès de la Société Chimique de France - 26-27 Juin 1986 à Plestin - Les Grèves - Brest -
France.
2. H. AMRI, M.M. EL GAIED et J. VILLIERAS, Nouvelle Synthèse d’un produit anticancéreux : la ±
sarkomycine. Cinquième journées de Chimie - 18 - 20 Décembre 1988 - HAMMAMET - Tunisie