CHOLESTÉROL
CANADA
1) CTFPHC 1994
Screening should be considered in all men aged 30 to 59 years; individual clinical judgement should be exercised
in all other cases (Recommandation C) For men 30 to 59 years old with a mean total cholesterol level of more
than 6.85 mmol/L or an LDL-C level of more than 4.50 mmol/L treatment is efficacious in reducing incidence of
CHD. (Recommandation B) For all other asymptomatic individuals the value of treatment has not been
demonstrated. (Recommandation C) Révision en cours?
2) The working group on hypercholesterolemia and other dyslipidemias (Canada)
2003: Routinely screen men over 40 years of age and women who are postmenopausal or over 50 years of age.
In addition screen those with: diabetes mellitus, risk factors such as hypertension, smoking or abdominal obesity;
a strong family history of premature cardiovascular disease; manifestation of hyperlipidemia or evidence of
symptomatic or asymptomatic atherosclerosis 2000 : Although there are no evidence-based recommendations
regarding the optimal frequency for screening, it is reasonable to suggest that asymptomatic patients be screened
every 5 years after the age of 40 for men and 50 for women
3) Association canadienne du diabete 2006
In adults, fasting lipids levels should be measured at the time of diagnosis of diabetes and then every 1 to 3 years
as clinically indicated.
ETATS-UNIS
1) USPSTF 2001
The U.S. Preventive Services Task Force (USPSTF) strongly recommends that clinicians routinely screen men
aged 35 years and older and women aged 45 years and older for lipid disorders and treat abnormal lipids in
people who are at increased risk of coronary heart disease. (Recommendation A)
AAFP has same recommandation (strongly recommands)
The USPSTF recommends that clinicians routinely screen younger adults (men aged 20 to 35 and women aged
20 to 45) for lipid disorders if they have other risk factors for coronary heart disease (Recommandation B)
(Diabetes., A family history of cardiovascular disease before age 50 years in male relatives or age 60 years in
female relatives, A family history suggestive of familial hyper-lipidemia. Multiple coronary heart disease risk
factors (e.g., tobacco use, hypertension).
The optimal interval for screening is uncertain. On the basis of other guidelines and expert opinion, reasonable
options include every 5 years, shorter intervals for people who have lipid levels close to those warranting
therapy, and longer intervals for low-risk people who have had low or repeatedly normal lipid levels
An age to stop screening is not established.
Screening may be appropriate in older people who have never been screened, but repeated screening is less
important in older people because lipid levels are less likely to increase after age 65 years
2) NCEPP III 2001 NCEPP: National cholesterol education program (USA)
In all adults aged 20 years or older, a fasting lipoprotein profile should be obtained once every five years.
(rien de nouveau sur dépistage dans update 2004)The American Heart Association has the same
recommandation
3) AACE 2002 American association of clinical endocrinologists
Screening for dyslipidemia is warranted for all adults up to 75 years of age regardless of CAD risk status and for
adults more than 75 years old who have multiple CAD risk factors (if they have good quality of life and no other
major life-limiting disease).
For adult more than 20 years of age with no CAD risk factors the screening should be done every 5 years. (more
often if CAD risk factors exist)