Mycobacterium Tuberculosis Lecture for Medical Students

Professor Ponndara ITH,
MD, GS, MPH, PhD
Chair, Academic Board
Faculty of Medicine, UHS
Honorary Professor, Faculty of Health,
University of Technology Sydney (UTS), Australia
Mycobacterium Tuberculosis
Medical Students (PI), Year 4, Semester 1, 2022-2023

❑Epidemiology of M.T
❑Clinical Aspects
❑Diagnostic
❑Management
❑Treatment and Prevention
Learning Objectives

Introduction
•Global situation:
•Public health concerns worldwide (WHO, 1993), one of
leading causes of communicable diseases
•Cambodia, one among the 30 countries with high burden
•Globally, 9.6 million new TB cases (6 million detected and
reported to WHO (1994)
•1.5 million people killed, 400, 000 were HIV positive
•HIV positive among TB patients 12%

•2015 last year of MDGs (Three main targets)
•Reduction of TB prevalence by 50%;
•Reduction of TB mortality by 50% and
•Reverse TB incidence
•2015-2020: SDGs
•The end TB strategy 2016-2035
•Reduction of TB mortality 90% by end 2030 and 95% by
the end of 2035
•Reduction of TB incidence by 80% by end 2030m
abdomen 90% by end 2035

•Cambodia situation
•>530 thousands detected and treated
•Incidence rate decreased 3.5% per year compared to
average global reduction of 1.5%
•Mortality rate decreased from 157/100,000 population in
1990 to 58/100,000 in 2924 (63% compared to target 50%
by end 2015)