Telechargé par majhouleseri

DOSS FEDI

publicité
Receptors of tissue of cardiovascular
system and the points of
attachement of drugs
The baroreceptor
The adrenergics receptors:
• Alpha-receptors are located on the arteries
(skin vessels, kidneys, gastrointestinal system).
• α1-adrenergic receptors are present in the
skin, the sphincters of gastrointestinal system,
kidney (renal artery) and brain.
• Alpha 2 receptors in the brain stem and in the
periphery inhibit sympathetic activity
Beta 1 receptors are located in the heart.
The beta 2 receptors are located in the
bronchioles of the lungs and the arteries of the
skeletal muscles
Alpha 2 receptors:
• Alpha 2 receptors in the brain stem and in the
periphery inhibit sympathetic activity and
reduce blood pressure.
Beta blockers effect:
Alpha1 blockers:
•Prazosin
•Terazosin
•Doxazosine
•Alfuzosin&Bunazosin
•Tamsulosin&Silodosin
Alpha2 blockers:
• Yohimbine
• Idozoxan
Beta 1 receptors:
 Beta 1 receptors are
located in the heart.
When Beta 1
receptors are
stimulated they
increase the heart rate
and increase the
heart's strength of
contraction or
contractility.
The beta 2 receptors:
The beta 2 receptors are located in the
bronchioles of the lungs and the arteries of
the skeletal muscles
β-2 receptors
Bronchial smooth
muscle
Smooth muscle
Bronchodilata
tion
relaxation
blood
oxygenation
Vasodilatation
Téléchargement
Explore flashcards