LARUE Lionel :: U1021 – UMR3347 :: Normal and Pathological Development of Melanocytes Unit : INSERM U1021 CNRS UMR3347 - Institut Curie Univeristé Paris 11 : Institut Curie INSERM U1021 CNRS UMR3347 Signalisation normale et pathologique : de l'embryon aux thérapies innovantes des cancers Bâtiment 110 Centre Universitaire 91405 ORSAY Cedex Director of the unit : : Simon SAULE (Directeur) et Lionel LARUE (Directeur Adjoint) Principal investigator : LARUE Lionel Email : [email protected] Phone number: +33 (0)1 69 86 71 07 Composition of research team : : LARUE Lionel (DR-INSERM, HDR) BONAVENTURE Jacky (DR-CNRS, HDR) DELMAS Véronique (DR-CNRS, HDR) GESBERT Franck (MCU, HDR) 5 Recent publications of the research team : : Gallagher, S.J*, Rambow, F*, Kumasaka, M*, Champeval, D., Bellacosa, A., Delmas, V. and Larue, L. (2013). Beta-catenin inhibits melanocyte migration but induces melanoma metastasis. Oncogene 32, 2230-2238. PMID:22665063. Berlin, I., Denat, L., Steunou, A.L., Puig, I., Champeval, D., Goodall, J., Bonvin, E., Bourgeois, Y., Delmas, V., Davidson, I., Nieto, L., Goding, C.R. and Larue, L.(2012). Brn-2 affects proliferation of melanocyte lineage during mouse development. Mol Cell Biol. 32:1237-47. PMID:22290434 Luciani, F., Champeval, D., Herbette, A., Denat, L., Aylaj, B., Martinozzi, M., Ballotti, R., Kemler, R., Goding, C.R., De Vuyst, F., Larue, L.* & Delmas, V.* (2011). Biological and Mathematical Modeling of Melanocyte Development. Development (2011) 138, 3943-3954. PMID:21862558 *Co-last authors. PMID:21862558 Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D., Bartolomei, M., Rambow, F., Bassi, M.R., Bruno, T., Fanciulli, M., Renner, C., Klein-Szanto, A.J., Matsumoto, Y., Kobi, D., Davidson, I., Alberti, C., Larue L. and Bellacosa, A. (2011) DNA demethylation and protection from hypermethylation by TDG in mammalian development. Cell 146:67-79. PMID:21722948.