Master of Science in Medical Biology 2011-2012 The Master program has the minimum duration of 3 semesters and comprises 90 ECTS : - 21 ECTS : Compulsory courses - 15 ECTS : Optional courses - 9 ECTS : First step project - 45 ECTS : Personal research project (Master thesis) Autumn Semester (semester 1) Course Hours per semester Teaching Staff C E/S PW ECTS Credits Compulsory Cellular biology Immunology and cancer Staub O. Luther S. 12 20 4 6 1.5 3 Cardiovascular diseases Diviani D. 20 4 3 Volterra A. 18 4 2.5 Thorens B. Kunz S. 16 18 4 4 3 3 Kohler S. 2 Diviani D. 12 From memory to memory loss: Alzheimer's disease Metabolic diseases Microbiology Publish or Perish: How to increase the impact of your research by a patent ? Intracellular signalling Total Optional (choice -> 3 credits) LTK1 Module: Training in Animal Experimentation** Introduction to clinical research module (EH) Berthonneche C., Pedrazzini T. Tappy L. Pratical project First step project Staub O. Total 0.5 4 1.5 18 20 20 3 20 20 3 282 9 30 Abbreviations C = Course E/S = Exercise/Seminar PW = Practical Work Page 1 of 4 / 09.02.2012/OS/jv Sous réserve de modifications Master of Science in Medical Biology 2011-2012 Spring Semester (semester 2) Course Compulsory, common core Introduction to clinical medicine Biostatistics and Bioinformatics Total Teaching Staff Bonny O. Diviani D. Hours per ECTS semester Credits C E/S PW 18 36 4 3 One study path among the following four: Immunology and Cancer Basic immunology Autoimmunity, allergy and immune response to infections Basic concepts in cancer biology Examples of tumor types Immunotherapy, vaccines, drug development Protein analysis and peptide-based assays - TP proteomics (26) - TP peptides (26) - TP proteomics 3D-modeling (6) Analysis of naive and activated lymphoid organs - 5 color flow cytometry and FlowJo analysis - Histology - Wrapping up Analysis of healthy and transformed tissues - Histology Problem-based learning Metabolism Adipocytes and obesity Experimental techniques : transgenesis and gene knockout Genomics of diabetes complications Hypothalamus and the interaction between metabolism and reproduction Metabolic adaptation to fasting: role of metabolic sensors Glucose as signal in metabolism regulation Mechanisms of hormone and neurotransmitter secretion Brain metabolism Lipid metabolism : theory and experimental techniques / Fetal programming Integrated metabolism of cholesterol Mitochondrion: role in energetics and cell signalling G-couple receptors and autonomic nervous system Metabolic syndrome / epidemiology Circadian rhythm and metabolism Page 2 of 4 / 09.02.2012/OS/jv Luther S. Luther S., Mayer A., Held W., Thome M., Tacchini F. Acha-Orbea H., Velin D., Zehn D., Perreau M. Fasel N., Petrova T., Constantinou A., Stamenkovic I. Hegi M., Nardelli D. Hantschel O. Romero P., Collin N., Levy F. Quadroni M. Servis C. Michielin O. Wilson A., Ronet C. Luther S., Debard N., Kraehenbuel J-P. Luther S., Kraehenbuel J-P. Kraehenbuel J-P., Bosman F. Luther S., Debard N., Kraehenbuel J-P., 12 22 2 17 1 17 1 7 1 11 1 18 2 58 6 6 16 8 5 Widmann C. Giusti V. 4 2 12 Hummler E. 4 2 Chrast R. 4 2 Pralong F. 4 2 Thorens B. 4 2 Thorens B. 4 2 Regazzi R. 4 Pellerin L. 4 2 Tappy L. 4 2 Widmann C. 4 1 Raddatz E. 4 2 Diviani D. 4 2 Vollenweider P. Gatfield D. 4 2 2 2 Sous réserve de modifications Master of Science in Medical Biology 2011-2012 Neurosciences Neuron-glia biology Introduction to Psychiatric Neuroscience Brain Development Modulation of synaptic transmission Neuronal death occuring naturally and in pathological situations Sensory functions Pharmacological Sciences Development of therapeutics Development of drugs : practical aspects Drug design Drug discovery / High through put screens Fundamental Principles: Pharmacokinetics / Pharmacogenomics Pharmacological treatment of metabolic disorders Principles of chemotherapy : Infectious diseases Principles of chemotherapy: Cancer Regulation and regulatory agencies Volterra A. Volterra A., Bezzi P., Pellerin L., Tiret P., Tschudi-Monnet F. Do K., Boutrel B., Preismann D., Marquet P., Eap C. Cardinaux J.-R., Hornung J.-P., Chrast R., Lebrand C., Arsenijevic Y. Fasshauer D., Lüthi A., Stoop R., Martin J.-L., Pralong E. Toni N., Puyal J., Widmann C., Hirt L., Moore D. Welker E., Hornung J.-P., Decosterd I., Murray M., Broillet M.-C., Croquelois M.-C., Gosselin R.-D. 12 18 2 18 2 16 4 14 2 14 2 24 Broillet M.-C. Broillet M.-C. Besseghir K. Scapozza L. Scheer A. 10 4 4 4 Firsov D. 10 2 2 6 6 2 2 2 6 2 20 2 8 2 Gachon F. Staub O. Katanaev V. Schild L. Kellenberger S. System Pharmacology: Cardiovascular Cotecchia S. pharmacology Diviani D. Cotecchia S., System Pharmacology: Neuropharmacology Kellenberger S., Eap C. System Pharmacology: Endocrine pharmacology Hummler E. Staub O., Broillet M.Seminars on Drug Discovery & Development C. Toxicology Broillet M.-C. Visit of an industrial pharmaceutical research Staub O., center Broillet M.-C. Inflammation and cancer: role of reactive oxygen Felley-Bosco E. species Transgenic mice and their application in Hummler E. biomedical research 12 12 8 2 5 10 10 Total per study path Compulsory personal research project Personal Research Project - Master thesis Page 3 of 4 / 09.02.2012/OS/jv 15 Staub O. 280 15 Sous réserve de modifications Master of Science in Medical Biology 2011-2012 Semester 3 Course Compulsory personal research project Personal Research Project - Master thesis Page 4 of 4 / 09.02.2012/OS/jv ECTS Credits 30 Sous réserve de modifications