6th Autophagy Scientific Days organized by CFATG Wednesday October 12

6th Autophagy Scientific Days organized by CFATG
BORDEAUX – 2016 – CFATG6
Wednesday October 12th
13h30-15h00 Registration
15h00-15h15 Welcome address by CFATG president - Mathias Faure
and local committee coordinator – Nadine Camougrand
15h15-16h00 Keynote session I :
Dr Terje Johansen
(University of Tromso, Norway)
Title: TBA
16h00-16h30 Session I : REGULATION AND SIGNALING
Session Chairs : Muriel Priault (Institut de Biochimie et Génétique
cellulaires, UMR 5095, Bordeaux) ; Raul Duran (Group Metabolism and Cell
Signaling, IECB, U1218 INSERM, Bordeaux)
16h00-16h15 Amélie Bernard (University of Michigan, USA)
Identification and characterization of pathways controlling the
expression of ATG genes
16h15-16h30 Elise Jacquin (The Babraham Institute, UK)
"Cells, Drugs and Vacuoles": A story of non-canonical autophagy
16h30-17h00 Coffee Break
17h00-18h00 Session I : REGULATION AND SIGNALING
17h00-17h15 Céline Jenzer (I2BC, CNRS, Gif-sur-Yvette)
Determination of functional specificity of LC3 proteins during
phagocytosis of apoptotic cells in embryo

17h15-17h30 Virginie Hubert (Medical University of Vienna, Autriche)
LAMP-2 is required to incorporate syntaxin 17 into the
autophagosome and mediate their fusion
17h30-17h45 Ghita Ghislat (Cambridge Institute for Medical Research,UK)
Annexins: new regulators of autophagic trafficking under starvation
17h45-18h00 Flash Talks Session I:
Session Chair : Sophie Pattingre (Institut de Recherche en Cancérologie
de Montpellier)
-!Florian Beaumatin (Beatson institute for cancer research, Glasgow,
UK)
mTOR requires DRAM1 to sense amino acids
-!Ana Maria Negulescu (Centre Léon Bérard - Centre de recherche en
cancérologie, Lyon)
Kremen-1 receptor functions as a putative tumor suppressor in breast
cancer by inducing autophagic cell death in absence of its ligand
Dickkopf-1
-!Mouradi El Hout (Institut Necker-Enfants Malades, Université Paris V -
Paris Descartes, Paris)
Role of AUTOPHAGY in CANCER STEM CELLS: From cytoprotection to
metabolic reprogramming
-!Clément Mazouffre (Laboratoire Homéostasie Cellulaire et
Pathologies, Université de Limoges)
Survival in colorectal cancer: collaboration between BDNF/TrkB and
autophagy pathways
18h00-21h00 Welcome cocktail and Poster Session I
Thursday October 13th
09h00-10h15 Session II : PATHOPHYSIOLOGY
Session Chairs : Benjamin Dehay (Institut des Maladies
Neurodégénératives CNRS UMR 5293 – Université de Bordeaux) ; Iban
Seiliez (UMR1419 INRA-UPPA NuMeA, St Pée sur Nivelle)
09h00-09h15 Carole Kretz-Remy (Institut NeuroMyoGène, Université Claude
Bernard- Lyon I, Villeurbanne)
NFKB is a master regulator of protein quality control in response to
protein aggregation stresses via autophagy modulation
09h15-09h30 Nicolas Charlet-Berguerand (Institut de Génétique et de Biologie
Moléculaire et Cellulaire, Université de Strasbourg)
The C9ORF72/ SMCR8 complex is a GDP/GTP exchange factor for
Rab GTPases and regulates autophagy

09h30-09h45 Hortense De Calbiac (Institut du Cerveau et de la Moelle épinière,
Paris)
C9ORF72 rescues the loss of function of the autophagy initiator
p62/SQSTM1
09h45-10h00 Jeanne Perez (Institut des Maladies Métaboliques et
Cardiovasculaires, Université Paul Sabatier, Toulouse)
Oxidative stress by monoamine oxidase-A impairs transcription
factor-EB activation and autophagosome clearance leading to
cardiomyocyte necrosis and heart failure
10h00-10h15 Marouane Kheloufi (Centre de Recherche Cardiovasculaire,
Université Paris Descartes, Paris)
Endothelial autophagy is required for atheroprotective signaling
10h15-10h45 Coffee Break
10h45-11h30 Keynote session II :
Dr Claudine Kraft
(University of Vienna, Austria)
EMBO Young Investigator Lecture
Title: Regulation and Signaling in Autophagy: Atg1/ULK1 Kinase
and Friends
11h30-11h45 Flash Talks Session II:
Session Chair : Sophie Pattingre (Institut de Recherche en Cancérologie
de Montpellier)
-!Jana Alazzaz (INSERM U866, Université Bourgogne Franche-Comté ;
Dijon)
Resveratrol treatment controls Salmonella Typhimurium and adherent-
invasive Escherichia coli persistence within intestinal epithelial cells
in an autophagy-dependent manner
-!Brieuc Perot (Institut Pasteur, Paris)
Autophagy represses the early interferon beta response to influenza A
virus, leading to a reduced interferon stimulated gene expression
following infection
-!Mickael Michaud (Institut Bergonié, Bordeaux)
Autophagy impacts the immune response to cancer treatments
-!Avédis Torossian (Centre de Recherche en Cancérologie de Toulouse,
Université Paul Sabatier, Toulouse)
Targeting Bcl-2 in ALK+ ALCL: at the crossroads between autophagy
and apoptotic cell death
11h45-14h30 Lunch and Poster Session II

14h30-15h15 Keynote session III :
Dr Kevin Ryan
(University of Glasgow, Scotland)
Title: Autophagy in cell death and cancer
15h15-16h00 Session III : CANCER
Session Chairs : Mojgan Djavaheri-Mergny (INSERM U1218, Institut
Bergonié, Bordeaux); Marion Bouchecareilh (UMR 5095, Institut de
Biochimie et Génétique cellulaires, Bordeaux)
15h15-15h30 Jean-Max Pasquet (U1035 INSERM, Université de Bordeaux)
Chronic myeloid leukemia progenitor cells require autophagy when
leaving hypoxia-induced quiescence
15h30-15h45 Magali Humbert (Institute of Pathology, Division of Experimental
Pathology, Berne, Switzerland)
P73-DAPK2-ATG5 Pathway in Acute Promyelocytic Leukemia
Therapy
15h45-16h00 Ada Nowosad (Centre de Recherche en Cancérologie de Toulouse,
Université Paul Sabatier, Toulouse)
Role of p27 in autophagy regulation in response to amino acid
deprivation
16h00-16h30 Coffee Break and Vote for best poster and for best flash talk
16h30-17h00 Session III : CANCER
16h30-16h45 Kelly Airiau (Institut Bergonié, Université de Bordeaux)
All-trans retinoic acid promotes p62 accumulation and potentiates
TRAIL-induced extrinsic apoptosis in acute promyelocytic leukemia
16h45-17h00 Aurélien Schwob (Centre International de Recherche en
Infectiologie, Ecole Normale Supérieure, Lyon)
HTLV1 Tax-induced NF-kB activation is regulated by selective
autophagy receptors at autophagic membranes
17h00-18h00 Annual General CFATG Meeting (CFATG Members only)
18h00-20h00 Free time
20h00 Gala Dinner
At “ Salons du Palais de la Bourse ” ►

Friday October 14th
09h00-10h15 Session IV : INFECTION & IMMUNITY
Session Chairs : Harald Wodrich (Laboratoire de microbiologie
Fondamentale et Pathogénicité, Université de Bordeaux) ; Frédéric Gros
(Institut de biologie moléculaire et cellulaire, Strasbourg)
09h00-09h15 Hoa Mai Nguyen (DIMNP-UMR 5235 CNRS, Université de Montpellier)
Important role of autophagy-related protein TgATG9 for parasite
survival in their host
09h15-09h30 Pauline Verlhac (Centre International de Recherche en
Infectiologie, Université Claude Bernard - Lyon I, Lyon)
A new regulator of autophagosome maturation
09h30-09h45 Charlotte Montespan (Laboratoire de microbiologie Fondamentale
et Pathogénicité, Université de Bordeaux)
Adenoviruses control autophagy during cell entry through a
conserved PPxY motif
09h45-10h00 Florent Arbogast (Institut de biologie moléculaire et cellulaire,
Strasbourg)
ATG5 is required for the constitution of the immune synapse after B
cell receptor engagement, and for the subsequent presentation of
immobilized antigens
10h00-10h15 Amandine Serrano (Centre de biophysique moléculaire, Orléans)
During efficient Anti-RetroViral (ARV) therapy, the expression of
GALIG and its interacting partners involved in macroautophagy are
deregulated
10h15-10h45 Coffee Break & Vote for best short talk
10h45-11h15 Autophagy Network (COST)
Dr Caty Casas Louzao :
Chair of the COST Action: TRANSAUTOPHAGY
(Universitat autonoma de Barcelona, Spain)
11h15-11h45 Awards: best « short talk », best « poster » and best «flash talk »
12h00 End of meeting (Lunch Box before departure)