Vascular Imaging of Prostate Cancer

Vascular Imaging of
Prostate Cancer
57TH JOURNEES FRANCAISES DE RADIOLOGIE 2009
Prostate Cancer
ROBERT L. BARD, MD
DIRECTOR
BIOFOUNDATION FOR ANGIOGENESIS
NEW YORK CITY
VITO CANTISANI, MD-FRANCESCO DRUDI, MD
UNIVERSITY HOSPITAL ROME

OBJECTIVES
•
QUANTIFY TUMOR AGGRESSION
•
QUANTIFY TUMOR AGGRESSION
BY VASCULAR DENSITY DATA
•DEMONSTRATE RECURRENCE AS
CANCER NEOVASCULARITY
•DOCUMENT TREATMENT SUCCESS BY
VASCULARITY REGRESSION

PSA - NEW STATUS
•
PAST PREDICTOR OF CANCER
•
PAST PREDICTOR OF CANCER
•CURRENTLY PREDICTS BPH
•POST SURGICAL MARKER
(RISE AFTER TREATMENT INDICATES
POSSIBLE TUMOR RECURRENCE
IN PROSTATE OR ELSEWHERE)
STAMEY T ET AL
JOURNAL OF UROLOGY 2004

S-MRI/EC-MRI ACCURACY
•
2009 ACRIN STUDY
•
2009 ACRIN STUDY
•NO DIFFERENCE IN ACCURACY
FOR STAGING BETWEEN S-MRI,
EC-MRI AND STANDARD MRI
MULTICENTER STUDY 134 PATIENTS

DIAGNOSTIC IMAGING WITH
DOPPLER, CE-US & DCE-MRI
OF RECURRENT CANCER
NON SPECIFIC: CT, MRI, PET, SPECT,
S-MRI AND NON- DOPPLER US
96% ACCURACY 3D-PDS/DCE-MRI
2009 109TH AM ROENTGEN RAY