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+#",-(#)0 ,)0 ."#/(."I,)H0 %D/-#)&H30 C’est$ une$ notion$ à$ bien$ retenir$ car$ quand$ on$
utilise$ les$ corticoïdes$ pendant$ longtemps,$ il$ faut$ arrêter$ progressivement$ le$
traitement$pour$que$les$corticosurrénales0se$remettent$progressivement$en$route$
et$ que$ l’on$ n’ait$ pas$ une$ insuffisance$ surrénalienne$ aiguë$ au$ moment$ de$ l’arrêt.0
T)#/D(%H0."#/(."I,)H0,)0HX%/FYH)0R&"K-)%/0+)-0&NDE)0FX+"/FD&D$"*FX+"+FXHD(#)0
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HX%/FYH)0K-(0R&"K-)%/0R)D-."-+0&NDE)0FX+"/FD&D$"*FX+"+FXHD(#)Q0(&0JD-,#D0M/#)0
/#YH0L('(&D%/0D-0$"$)%/0,)0&ND##M/0,-0/#D(/)$)%/0+"-#0GL(/)#0&D0H-#L)%-)0,N-%)0
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0
Corticoïde
Effet anti-
inflammatoire
1/2 vie
biologique
Rétention
hydrosodée
Freination
axe H.H.S.
Hydrocortisone
1
8 à 12 h
1
1
Cortisone
0,8
8 à 12 h
1
1
Prednisone (Cortancyl®)
4
12 à 36 h
0,8
4
Prednisolone (Solupred®)
4
12 à 36 h
0,8
4
Méthylprednisolone (Médrol®)
5
12 à 36 h
0,5
5
Triamcinolone (Kénacort®)
5
12 à 36 h
0,1
5
Dexaméthasone (Décadron®)
25
36 à 54 h
0,1
50
Bétaméthasone (Célestène®)
25
36 à 54 h
0,1
50
Cortivazole (Altim®)
60
>60 h
0,1
>50
0
0
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