International meeting on mouse models of skin cancer
Montpellier - May 25-28, 2014
Chairman: C. BLANPAIN, Free University of Brussels, Belgium
9.00 am - CONFERENCES
Target genes and target cells in mouse models of skin cancer - A. BALMAIN, UCSF, San Francisco, USA (30’)
Specific roles for BRAF and CRAF in NRAS-induced mouse melanoma - A. EYCHENE, Institut Curie, Orsay,
France (30’)
Regulation and dysregulation of epidermal stem cells - K. JENSEN, BRIC, Copenhagen, Denmark (30’)
10.30 am - SELECTED TALK
> Akt signalling leads to stem cell activation and promotes tumour development in epidermis –
J.M. PARAMIO, CIEMAT, Madrid, Spain (15’)
10.45 am – Coffee break
11.00 am - CONFERENCES
Genetic analysis of microRNA functions in squamous cell carcinoma - R. YI, University of Colorado,
Boulder, USA (30’)
Cellular and molecular mechanisms in stem cell-driven sebaceous skin tumor initiation – C. NIEMANN,
Cologne University, Cologne, Germany (30’)
12.00 am - SELECTED TALKS
> Role of EMT transcription factors in skin epidermis – B. DE CRAENE, VIB Inflammation Research Center/
Ghent University, Ghent, Belgium (15’)
> The multifunctional E4F1 protein links metabolism to epidermal stem cell maintenance – L. LE CAM,
Inserm U896 – IRCM, Montpellier, France (15’)
12.30 pm - Lunch
Chairman: E. WAGNER, CNIO, Madrid, Spain
2.00 pm - CONFERENCES
Relevance of skin and oral squamous cell carcinoma cancer stem cell heterogeneity in primary tumor
growth and metastasis –S. AZNAR BENITAH, IRB, Barcelona, Spain (30’)
Role of AP-1 proteins in skin cancer squamous cell carcinoma development - E. WAGNER, CNIO, Madrid,
Spain (30’)
Mechanisms regulating stemness in skin cancers – C. BLANPAIN, Free University of Brussels, Belgium (30’)
Investigating new targets of p63 during the pathogenesis of squamous cell carcinoma - W. KEYES, CRG,
Barcelona, Spain (30’)
4.00 pm – POSTER SESSION & Coffee break
5.00 pm - SELECTED TALKS
> Epithelial to mesenchymal transition controls tumor heterogeneity and stemness in skin cancers–
D. NASSAR, Free University of Brussels, Brussels, Belgium (15’)
> Loss of TGFbeta signaling and oncogenic BRAF activation in Lgr5+ stem cells drive rapid cutaneous
squamous cell carcinoma – G. INMAN, Jacqui Wood Cancer Center, Dundee, UK (15’)
> CD98hc (SLC3A2) loss protects against Ras-driven tumorigenesis through modulation of Integrin-mediated
mechanotransduction – C. FERAL, IRCAN, Nice, France (15’)
> Generation of new mouse models to determine molecular mechanisms involved in skin squamous cell carcinoma
progression and metastasis – P. MUñOZ MORUNO, Bellvtige Biomedical Research Institute, IDIBELL,
Barcelona, Spain (15’)