Projets financés Appel à projets 2009 Projets libres "Recherches Biomédicales porteur projet Patrick MEHLEN Pierre HAINAUT Alain PUISIEUX Sébastien PFEFFER Organisme d'appartenance titre projet Cancéropôle Centre Léon Bérard - LYON The dependence receptor TrkC and its ligand NT-3 in neuroblastoma, from basic research to drug therapy CLARA Functional basis of genetic susceptibility due to a common Centre International de Recherche sur le polymorphism in TP53 intron 3: effect on alternative Cancer - LYON splicing and on the synthesis of ΔNp53, an isoform which counteracts p53 function. CLARA Centre Léon Bérard - LYON Reactivation of the embryonic TWIST gene: a link between early phases of tumor progression and metastatic dissemination CLARA Institut de biologie moléculaire et cellulaire du CNRS - STRASBOURG Characterization of EBV and cellular microRNAs variations in Lymphoproliferative Disorders: implication for early diagnosis and development of therapeutical tools GE INCa - AAP2009 Projets libres recherches biomédicales Cécile ROCHETTE-EGLY Institut de Génétique et Biologie Moléculaire et Cellulaire - ILLKIRCH Crosstalk between the non-genomic (activation of kinase cascades) and genomic effects of Retinoic Acid : deregulation in cancers GE Evi SOUTOGLOU Institut de Génétique et Biologie Moléculaire et Cellulaire - ILLKIRCH Nuclear architecture and chromatin structure in genome integrity and DNA repair GE Philippe JAY Institut de génomique fonctionnelle de Montpellier - MONTPELLIER Stem cells, self-renewall and cancer GSO André PELEGRIN Patrick RAYNAL Robin FAHRAEUS Institut de Recherche en Cancérologie de Radioimmunotherapy of small peritoneal carcinomatosis Montpellier, INSERM U896 - CRLC Val using low energy electrons emitters d’Aurelle - MONTPELLIER GSO CHU Purpan - TOULOUSE Signaling pathways activated by oncogenic mutations of the tyrosine phosphatase Shp2: Quantitative phosphoproteomics and functional analysis. GSO INSERM U940 - Institut de génétique moléculaire Paris The role of the p53 mRNA-Mdm2 interaction in the DNA damage pathway. IDF INCa - AAP2009 Projets libres recherches biomédicales Olivier BERNARD Guido KROEMER Laurence ZITVOGEL James P DI SANTO Jean-Henri BOURHIS Abdel-Majid KHATIB Hôpital Necker - Enfants malades APHP - PARIS Functional analyses and modeling of TET2-associated myeloid malignancies IDF Prognostic and predictive impact of immunogenic cancer INSERM U848 - Institut Gustave Roussy cell death, tumor infiltration by lymphocytes and genes VILLEJUIF controlling the anticancer immune response IDF Institut Gustave Roussy -VILLEJUIF Role of the inflammasome in the transition between tolerance and inflammation during chemo-or-radiotherapy of cancer IDF Institut Louis Pasteur - PARIS Human Anti-Tumor Immune Responses (HATIR) in Human Immune System (HIS) mice IDF Institut Gustave Roussy -VILLEJUIF Graft vs leukemia potential of allogeneic NK cells in human hematopoietic transplantation for the treatment of residual disease in leukemias IDF Laboratoire de Pharmacologie Expérimentale et Clinique - Institut de Génétique Moléculaire - PARIS Protein precursors maturation by the convertases (PCs) in angiogenesis and lymphangiogenesis during development and tumorigenesis. IDF INCa - AAP2009 Projets libres recherches biomédicales Michelle DEBATISSE Catherine THIEBLEMONT Philippe CHAVRIER CAMONIS Jacques Jacques GHYSDAEL Olivier DELATTRE Institut Curie - PARIS Replication profile, S Phase Control and Common Fragile Site Instability IDF Hôpital Saint-Louis - APHP - PARIS Biomarkers identification in CNS relapse of diffuse large B cell lymphomas IDF Institut Curie - PARIS Roles of microtubules and microtubule post-translational modifications during tumor cell invasion IDF Institut Curie - PARIS The Ral GTPases are new regulators of autophagy. Connections with their roles in tumorigenesis and cell survival IDF UMR 146 - CNRS - Institut Curie Dissection of molecular pathways essential to leukemia initiating cell function in T-cell acute lymphoblastic leukemia IDF Institut Curie - PARIS Systems biology of Ewing’s tumor: high-throughput phenotyping and mathematical modeling IDF INCa - AAP2009 Projets libres recherches biomédicales Karim BENIHOUD Claude BOCCARA Simon WAIN-HOBSON Anne-Odile HUEBER Bertrand NADEL Institut Gustave Roussy -VILLEJUIF Potentialization of iodine 131 metabolic radiotherapy after gene transfer of sodium/iodide symporter IDF Ecole supérieure de physique et de chimie industrielles - Institut Langevin PARIS Optical diagnostics for surgery in mammary oncology IDF Institut Louis Pasteur - PARIS Cytidine hyperediting of chromosomal DNA IDF Centre Antoine Lacassagne -NICE The regulation of membrane dynamics and posttranslational modification that define the plasticity of Fas receptor signalling in colorectal adenocarcinoma: potential biomarkers of rectal cancer treatments PACA Centre d’Immunologie de Marseille Luminy - MARSEILLE MYC-mediated oncogenesis in aggressive T-cell Acute Leukemia PACA INCa - AAP2009 Projets libres recherches biomédicales