Projets financés Appel à projets 2009 Projets libres "Recherches

Projets financés
Appel à projets 2009
Projets libres "Recherches Biomédicales
porteur projet Organisme d'appartenance titre projet Cancéropôle
Patrick MEHLEN Centre Léon Bérard - LYON The dependence receptor TrkC and its ligand NT-3 in
neuroblastoma, from basic research to drug therapy CLARA
Pierre HAINAUT Centre International de Recherche sur le
Cancer - LYON
Functional basis of genetic susceptibility due to a common
polymorphism in TP53 intron 3: effect on alternative
splicing and on the synthesis of ΔNp53, an isoform which
counteracts p53 function.
CLARA
Alain PUISIEUX Centre Léon Bérard - LYON
Reactivation of the embryonic TWIST gene: a link
between early phases of tumor progression and
metastatic dissemination
CLARA
Sébastien PFEFFER Institut de biologie moléculaire et
cellulaire du CNRS - STRASBOURG
Characterization of EBV and cellular microRNAs
variations in Lymphoproliferative Disorders: implication for
early diagnosis and development of therapeutical tools
GE
INCa - AAP2009 Projets libres recherches biomédicales

Cécile ROCHETTE-EGLY Institut de Génétique et Biologie
Moléculaire et Cellulaire - ILLKIRCH
Crosstalk between the non-genomic (activation of kinase
cascades) and genomic effects of Retinoic Acid :
deregulation in cancers
GE
Evi SOUTOGLOU Institut de Génétique et Biologie
Moléculaire et Cellulaire - ILLKIRCH
Nuclear architecture and chromatin structure in genome
integrity and DNA repair GE
Philippe JAY Institut de génomique fonctionnelle de
Montpellier - MONTPELLIER Stem cells, self-renewall and cancer GSO
André PELEGRIN Institut de Recherche en Cancérologie de
Montpellier, INSERM U896 - CRLC Val
d’Aurelle - MONTPELLIER
Radioimmunotherapy of small peritoneal carcinomatosis
using low energy electrons emitters GSO
Patrick RAYNAL CHU Purpan - TOULOUSE
Signaling pathways activated by oncogenic mutations of
the tyrosine phosphatase Shp2: Quantitative
phosphoproteomics and functional analysis.
GSO
Robin FAHRAEUS
INSERM U940 - Institut de génétique
moléculaire -
Paris
The role of the p53 mRNA-Mdm2 interaction in the DNA
damage pathway. IDF
INCa - AAP2009 Projets libres recherches biomédicales

Olivier BERNARD Hôpital Necker - Enfants malades -
APHP - PARIS
Functional analyses and modeling of TET2-associated
myeloid malignancies IDF
Guido KROEMER INSERM U848 - Institut Gustave Roussy
VILLEJUIF
-
Prognostic and predictive impact of immunogenic cancer
cell death, tumor infiltration by lymphocytes and genes
controlling the anticancer immune response
IDF
Laurence ZITVOGEL Institut Gustave Roussy -VILLEJUIF
Role of the inflammasome in the transition between
tolerance and inflammation during chemo-or-radiotherapy
of cancer
IDF
James P DI SANTO Institut Louis Pasteur - PARIS Human Anti-Tumor Immune Responses (HATIR) in
Human Immune System (HIS) mice IDF
Jean-Henri BOURHIS Institut Gustave Roussy -VILLEJUIF
Graft vs leukemia potential of allogeneic NK cells in
human hematopoietic transplantation for the treatment of
residual disease in leukemias
IDF
Abdel-Majid KHATIB
Laboratoire de Pharmacologie
Expérimentale et Clinique - Institut de
Génétique Moléculaire - PARIS
Protein precursors maturation by the convertases (PCs) in
angiogenesis and lymphangiogenesis during development
and tumorigenesis.
IDF
INCa - AAP2009 Projets libres recherches biomédicales

Michelle DEBATISSE Institut Curie - PARIS Replication profile, S Phase Control and Common Fragile
Site Instability IDF
Catherine THIEBLEMONT Hôpital Saint-Louis - APHP - PARIS Biomarkers identification in CNS relapse of diffuse large B
cell lymphomas IDF
Philippe CHAVRIER Institut Curie - PARIS Roles of microtubules and microtubule post-translational
modifications during tumor cell invasion IDF
CAMONIS Jacques Institut Curie - PARIS
The Ral GTPases are new regulators of autophagy.
Connections with their roles in tumorigenesis and cell
survival
IDF
Jacques GHYSDAEL UMR 146 - CNRS - Institut Curie
Dissection of molecular pathways essential to leukemia
initiating cell function in T-cell acute lymphoblastic
leukemia
IDF
Olivier DELATTRE Institut Curie - PARIS Systems biology of Ewing’s tumor: high-throughput
phenotyping and mathematical modeling IDF
INCa - AAP2009 Projets libres recherches biomédicales

Karim BENIHOUD Institut Gustave Roussy -VILLEJUIF Potentialization of iodine 131 metabolic radiotherapy after
gene transfer of sodium/iodide symporter IDF
Claude BOCCARA Ecole supérieure de physique et de
chimie industrielles - Institut Langevin -
PARIS
Optical diagnostics for surgery in mammary oncology IDF
Simon WAIN-HOBSON Institut Louis Pasteur - PARIS Cytidine hyperediting of chromosomal DNA IDF
Anne-Odile HUEBER Centre Antoine Lacassagne -NICE
The regulation of membrane dynamics and post-
translational modification that define the plasticity of Fas
receptor signalling in colorectal adenocarcinoma: potential
biomarkers of rectal cancer treatments
PACA
Bertrand NADEL Centre d’Immunologie de Marseille
Luminy - MARSEILLE
MYC-mediated oncogenesis in aggressive T-cell Acute
Leukemia PACA
INCa - AAP2009 Projets libres recherches biomédicales