Towards the utilization of cannabinoids as anti

Towards the utilization of
cannabinoids as anti-cancer
agents
agents
Guillermo Velasco
Sestri Levante September 2015

Anti-cancer activity of cannabinoids
Munson Munson et al.et al. (1975) (1975) Antineoplastic activity of cannabinoidsAntineoplastic activity of cannabinoids
J. Natl. Cancer Inst. 55, 597J. Natl. Cancer Inst. 55, 597
--
602602
J.
Natl.
Cancer
Inst.
55,
597J.
Natl.
Cancer
Inst.
55,
597
602602

V
ehIcle THC Before THC
A
fter THC
Galve-Roperh et. al. Nat. Med. 2000

Cannabinoids exhibit anti-tumor activity in many different
animal
models
of
cancer
Glioma
animal
models
of
cancer
Melanoma
Skin carcinoma
Skin
carcinoma
Lung cance
r
Hepatocellular carcinoma
Breast cancer
Pancreatic adenocarcinoma
Prostate cancer
Leukaemia

A
ntitumora
l
action of cannabinoids
Velasco et al. Nat Rev Cancer (2012)