LES PUBLICATIONS MOLECULAR AND CELLULAR BIOLOGY OF TOXOPLASMA GONDII Inserm U1019 - CNRS UMR 8204 University Lille 1 - University Lille 2 Institut Pasteur de Lille affiliated to IFR 142 Responsable Stanislas TOMAVO 00 33 3 20 87 74 29 2010 Deruy E, Gosselin K, Vercamer C, Martien S, Bouali F, Slomianny C, Bertout J, Bernard D, Pourtier A, Abbadie C. MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes. PlosOne, 2010, 5:e12712. HumbertN, Navaratnam N, Augert A, Da Costa M, Martien S, Wang J, Martinez D, Abbadie C, Carling D, de Launoit Y, Gil J, Bernard D. Regulation of ploidy and senescence by the AMPK-related kinase NUAK1. EMBO J, 2010, 29:376-386. 2009 Gosselin K, Martien S, Pourtier A, Vercamer C, Ostoich P, Morat L, Sabatier L, Duprez L, T'kint de Roodenbeke C, Gilson E, Malaquin N, Wernert N, Slijepcevic P, Ashtari M, Chelli F, Deruy E, Vandenbunder B, De Launoit Y, Abbadie C. Senescence-associated oxidative DNA damage promotes the generation of neoplastic cells. Cancer Res, 2009, 69:7917-7925. Gosselin K, Deruy E, Martien S, Vercamer C, Bouali F, Dujardin T, Slomianny C, Houel-Renault L, Chelli F, De Launoit Y, Abbadie C. Senescent keratinocytes die by autophagic programmed cell death. Am J Pathol, 2009, 174:423-435. Humbert N, Martien S, Augert A, Da Costa M, Mauen S, Abbadie C, de Launoit Y, Gil J, Bernard D. A genetic screen identifies topoisomerase 1 as a regulator of senescence. Cancer Res, 2009, 69:4101-4106. Monet M, Gkika D, Lehen'kyi V, Pourtier A, Vanden Abeele F, Bidaux G, Juvin V, Rassendren F, Humez S, Prevarsakaya N. Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation. Biochim Biophys Acta, 2009, 1793:528-539. Sahin A, Vercamer C, Kaminski A, Fuchs T, Florin A, Hahne JC, Mattot V, Pourtier-Manzanedo A, Pietsch T, Fafeur V, Wernert N. Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes. Int J Oncol, 2009, 34:377-389. 2008 Furlan A, Vercamer C, Desbiens X, Pourtier, A. Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment. J Cell Physiol, 2008, 215:782-793. Molendi-Coste O, Mairesse J, Aubert N, Ghzili H, Abbadie C, Vaudry H, Gonzales B, Anouar Y, Vieau D, Breton C, Laborie C. Maternal perinatal undernutrition impairs chromaffin cells proliferation in the postnatal rat. Hormone Metab Res, 2008, 40:386-390. 2007 Martien S, Abbadie C. Acquisition of oxidative damage during senescence : the first step towards carcinogenesis. Annals New York Acad Sci, 2007, 1119:51-63. Zdanov S, Bernard D, Debacq-Chainiaux F, Martien S, Gosselin K, Vercamer C, Chelli F, Toussaint O, Abbadie C. Normal or stress-induced fibroblast senescence involves COX-2 activity. Exp Cell Res, 2007, 313:3046-3056. PhD Sébastien MARTIEN Directeur : C. Abbadie PhD "Biologie-Santé" Université de Lille Décembre 2009 Alessandro FURLAN Directeur : A. Pourtier PhD "Biologie-Santé" Université de Lille Décembre 2007