Chemistry versus Bio, Georges Massiot, CNRS, FR

Chemistry vs Bio
Concarneau, le 30 septembre 2011
Georges Massiot,
Unité mixte CNRS Pierre-Fabre
Epigenetic of Cancer
USR CNRS – Pierre Fabre n°3388
Epigenetic Targeting of Cancer
USR CNRS – Pierre Fabre n°3388

Georges Massiot l30 septembre 2011 Concarneau
IMarine resources
•Large, diverse, unlimited
•Unexplored
•May find uses in:
•Health
•Technologies (Bio)
•Energy
•Supply of raw materials
Epigenetic of Cancer
USR CNRS – Pierre Fabre n°3388
Epigenetic Targeting of Cancer
USR CNRS – Pierre Fabre n°3388

Georges Massiot l30 septembre 2011 Concarneau
IMarine resources and Health
•Health ?
•There is still need for new treatments
•To replace inefficient treatments
•To treat neglected diseases
•Solutions ?
•Chemistry (NCE)
•Biology (NBE)
•Biotechnologies
Epigenetic of Cancer
USR CNRS – Pierre Fabre n°3388
Epigenetic Targeting of Cancer
USR CNRS – Pierre Fabre n°3388

Georges Massiot l30 septembre 2011 Concarneau
IDrugs from Marine origin
•Vidarabine, Cytarabine
•ET-743 Yondelis (ectinascidin)
•Prialt
•Eribulin
Epigenetic of Cancer
USR CNRS – Pierre Fabre n°3388
Epigenetic Targeting of Cancer
USR CNRS – Pierre Fabre n°3388

Georges Massiot l30 septembre 2011 Concarneau
ISuccesses and failures
•Saxitoxin
•Discodermolide
•Girolline
Epigenetic of Cancer
USR CNRS – Pierre Fabre n°3388
Epigenetic Targeting of Cancer
USR CNRS – Pierre Fabre n°3388