9h00 FORUM du Centre Scienti�ique de Monaco Introduction Session du matin ; Chair: Renaud Grépin & Philippe Ganot 9h10 9h40 10h10 Vanessa Bednarz (Ecophysiologie) métabolisme/symbioses-nitrification “Diazotrophs: Key Players within the Coral Symbiosis.” Milica Vucetic (Hypoxie tumorale et métabolisme) métabolisme/transporteur “Genetic disruption of the cystine importer Xct (Slc7a11), essential for glutathion synthesis, supresses tumor cell growth in hypoxia.” Pause Café Rachid Benchaouir (LIA-BAHN) “Molecular strategies for muscular dystrophies.” 11h00 Sandy Giuliano (Mécanismes de résistance aux thérapies ciblées) “Lysosomotropism and drug resistance.” 10h30 11h30 12h25 thérapie ciblée thérapie ciblée LAURENT MEIJER ManRos Therapeutics “From the cell biology of marine invertebrates to the treatment of human diseases” Lunch Buffet Session de l’après-midi ; Chair: Didier Zoccola & Vincent Picco Víctor Planas-Bielsa (Biologie Polaire) big data /statistique “p-values are dead! A hitchhiker's guide to statistics in biology.” big data /clinique 14h15 Barbara Cappelli (Monacord) “Analysis of transplant results from the Eurocord/Monacord Registry: the Sickle Cell example.” microbiome 14h45 Maria Ciobanu (Ecosysteme Intestinal) “The development of the anemone Exaiptasia pallida as a new model for the study of host-pathogen interactions in humans” microbiome/transcriptomique 15h15 Jeroen van de Water (Ecophysiologie) “The composition and function of the gorgonian microbiome.” 13h45 15h45 Pause café Philippe Ganot (Physiologie) calcification/omique “Omics of the red coral Corallium rubrum : focus on calcification.” pH/calcification 16h45 Duygu Sevilgen (Physiologie) “Insight into biomineralization : what we can learn from poking microsensors into corals.” pH/cancer 17h15 Scott Parks (Hypoxie tumorale et métabolisme) “Hypoxia, pH regulation and cancer.” 16h15 17h45 18h00 Patrick Rampal La conclusion du président Discussions autour d’un cocktail